Human Cerebral Organoids Recapitulate Gene Expression Programs
Source Camp et al. · Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany · 10.1073/pnas.1520760112
Abstract
Camp et al. performed the first single-cell RNA-sequencing analysis of cerebral organoids, comparing transcriptional profiles to human fetal neocortex at 12–13 post-conception weeks. The study confirmed that organoid-derived neural progenitors and neurons recapitulate key gene expression programs of fetal cortical development, establishing scRNA-seq as a critical quality control benchmark.
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Attribution
This SOP was authored by Organthis based on the published method in Camp et al.. The originating laboratory holds no rights in this SOP and has not endorsed it unless marked Verified.
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