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934 protocols found

BRAIN

Publication-derived

Herpes Simplex Virus Infection Brain Organoids for Drug Screening

Source D'Aiuto et al., 2019 · University of Pittsburgh School of Medicine · DOI

Human iPSC Full SOP · 11 phases · QC included

Drug screening

Full SOP with Academic or a plan

BRAIN

Publication-derived

Schizophrenia and Neurodevelopmental Disorder Cerebral Organoids

Source Johnstone et al., 2019 · Centre for Clinical Brain Sciences, University of Edinburgh · DOI

Patient-Derived iPSC (chromosome 16p13.11 microduplication) Full SOP · 8 phases · QC included

Disease modelling

Full SOP with Academic or a plan

BRAIN

Publication-derived

Meningioma Brain Reference Datasets

Source Choudhury et al., 2022 · University of California, San Francisco · DOI

Primary human meningioma tissue Full SOP · 7 phases · QC included

Characterisation

Full SOP with Academic or a plan

BRAIN

Publication-derived

Traumatic Brain Injury Organoids with Electrical Pacing

Source Hu et al., 2024 · Academy of Medical Engineering and Translational Medicine, Tianjin University · DOI

Human ESC (H9-hESC) Full SOP · 9 phases · QC included

Disease modelling

Full SOP with Academic or a plan

BRAIN

Publication-derived

Glioblastoma Brain Organoids with Gene Editing

Source Wang et al., 2024 · German Cancer Research Center (DKFZ), Heidelberg, Germany and ShanghaiTech University, Shanghai, China · DOI

Human iPSC Full SOP · 6 phases · QC included

Drug screening

Full SOP with Academic or a plan

OTHER

Publication-derived

Head and Neck Squamous Cell Carcinoma Tumouroids

Source Driehuis et al., 2019 · Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht · DOI

Patient-Derived HNSCC and Adjacent Normal Tissue Full SOP · 7 phases · QC included

Drug screening

Full SOP with Academic or a plan

BRAIN

Publication-derived

Leigh Syndrome Brain 2D Cell Cultures

Source Inak et al., 2021 · Max Delbrück Center for Molecular Medicine (MDC), Berlin, Germany · DOI

Patient-Derived iPSC (Leigh syndrome, SURF1 mutations) Full SOP · 9 phases · QC included

Disease modelling

Full SOP with Academic or a plan

LIVER

Publication-derived

Malaria Liver Spheroids

Source Chua et al., 2019 · Novartis Institute for Tropical Diseases, Singapore · DOI

Human primary hepatocytes; Cynomolgus monkey primary hepatocytes Full SOP · 6 phases · QC included

Drug screening

Full SOP with Academic or a plan

EPITHELIAL

Publication-derived

Head and Neck Squamous Cell Carcinoma Epithelial Organoids

Source Driehuis et al., 2019 · Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), University Medical Center Utrecht · DOI

Human surgical resections and biopsies (normal oral mucosa and HNSCC patient-derived tissue) Full SOP · 4 phases · QC included

Drug screening

Full SOP with Academic or a plan

BRAIN

Publication-derived

Parkinson's Disease Midbrain Organoids for Regenerative Medicine

Source Kim et al., 2021 · Department of Biochemistry and Molecular Biology, College of Medicine, Hanyang University, Seoul, Republic of Korea · DOI

Human hESC and hiPSC Full SOP · 7 phases · QC included

Disease modelling

Full SOP with Academic or a plan

BRAIN

Publication-derived

Schizophrenia Cortical Organoids

Source Ye et al., 2017 · Johns Hopkins University School of Medicine; University of Pennsylvania; Hong Kong University of Science and Technology · DOI

Human iPSC, Patient-Derived iPSC (Schizophrenia with DISC1 mutation) Full SOP · 7 phases · QC included

Disease modelling

Full SOP with Academic or a plan

BRAIN

Publication-derived

Brain Organoids for Disease Modelling (2011)

Source Suga et al., 2011 · RIKEN Center for Developmental Biology, Kobe, Japan · DOI

Mouse embryonic stem cells (ES cells) Full SOP · 7 phases · QC included

Disease modelling

Full SOP with Academic or a plan

BRAIN

Publication-derived

Schizophrenia Brain Organoids (2023)

Source Kathuria et al., 2023 · Massachusetts General Hospital, Center for Genomic Medicine · DOI

Patient-Derived iPSC (schizophrenia); Patient-Derived iPSC (bipolar disorder) Full SOP · 10 phases · QC included

Disease modelling

Full SOP with Academic or a plan

BRAIN

Publication-derived

Meningioma Brain Tumouroids (2024)

Source Kim et al., 2024 · The Catholic University of Korea; Seoul St. Mary's Hospital · DOI

Patient-Derived Tissue (Meningioma) Full SOP · 7 phases · QC included

Drug screening

Full SOP with Academic or a plan

KIDNEY

Publication-derived

Kidney Spheroids for Drug Screening

Source Freedman et al., 2015 · Brigham and Women's Hospital, Harvard Medical School · DOI

Human iPSC, Human ESC Full SOP · 8 phases · QC included

Drug screening

Full SOP with Academic or a plan

BRAIN

Publication-derived

Parkinson's Disease Midbrain Organoids for Drug Screening (2021)

Source Zanetti et al., 2021 · Vienna University of Technology (TUW), Austria · DOI

Human iPSC Full SOP · 6 phases · QC included

Drug screening

Full SOP with Academic or a plan

BRAIN

Publication-derived

Glioblastoma Brain Organoids under Hypoxia

Source Hubert et al., 2016 · Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic · DOI

Patient-Derived Primary Glioblastoma, Xenografts, Genetically Engineered Glioma Models Full SOP · 9 phases · QC included

Disease modelling

Full SOP with Academic or a plan

LIVER

Publication-derived

Hepatoblastoma Liver Tumouroids with Single-Cell Profiling

Source Kluiver et al., 2023 · Princess Máxima Center for Pediatric Oncology · DOI

Patient-Derived Tumor Tissue (Hepatoblastoma) Full SOP · 7 phases · QC included

Drug screening

Full SOP with Academic or a plan

REPRODUCTIVE

Publication-derived

High-Grade Serous Ovarian Cancer Reproductive Tumouroids (RP-DS-18)

Source Hill et al., 2018 · Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School · DOI

30 days Patient-Derived Tumor Cells (High-Grade Serous Ovarian Cancer) Full SOP · 8 phases · QC included

Drug screening

RP-DS-18 Full SOP with Academic or a plan

BRAIN

Publication-derived

Alzheimer's Disease Cerebral Organoids with Electrophysiology (BN-DS-19)

Source Ghatak et al., 2019 · The Scripps Research Institute · DOI

56 days Patient-Derived iPSC (Alzheimer's Disease - Familial) Full SOP · 23 phases · QC included

Disease modelling

BN-DS-19 Full SOP with Academic or a plan

LIVER

Publication-derived

Liver Organoids for Regeneration and Long-Term Culture (LV-DS-18)

Source Peng et al., 2018 · Stanford University School of Medicine · DOI

180 days Primary mouse hepatocytes Full SOP · 5 phases · QC included

Disease modelling

LV-DS-18 Full SOP with Academic or a plan

INTESTINAL

Publication-derived

Rotavirus Infection Small Intestinal Models for Disease Modelling (IN-DS-16)

Source Saxena et al., 2016 · Baylor College of Medicine · DOI

14 days Human Primary Intestinal Epithelial Cells (Duodenal, Jejunal, and Ileal Biopsies) Full SOP · 13 phases · QC included

Disease modelling

IN-DS-16 Full SOP with Academic or a plan

LUNG

Publication-derived

Cystic Fibrosis Airway Models (AW-DS-15)

Source Firth et al., 2015 · The Salk Institute of Biological Studies · DOI

16 days Patient-Derived iPSC (Cystic Fibrosis - DF508 CFTR mutation) Full SOP · 7 phases · QC included

Disease modelling

AW-DS-15 Full SOP with Academic or a plan

BRAIN

Publication-derived

Parkinson's Disease Midbrain Organoids (2021) (BN-DS-21)

Source Jo et al., 2021 · Genome Institute of Singapore; National Neuroscience Institute; Duke-NUS Medical School · DOI

90 days Human ESC; Patient-Derived iPSC (Parkinson disease) Full SOP · 4 phases · QC included

Disease modelling

BN-DS-21 Full SOP with Academic or a plan