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934 protocols found
934 protocols found
LIVER
Publication-derived

Fatty Liver Disease Organoids with Single-Cell Profiling (LV-IF-23)

Source Hess et al., 2023 · Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA · DOI

Duration: 26 days Cell source: Human pluripotent stem cells (hPSCs) - H1 (WA01) and patient-derived iPSC4 Full SOP · 11 phases · QC included
Disease modelling
LV-IF-23 Full SOP with Academic or a plan
LIVER
Publication-derived

Liver Organoids for Regeneration and Disease Modelling (LV-DS-16)

Source Broutier et al., 2016 · Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge · DOI

Duration: 21 days Cell source: Adult primary hepatic stem cells (mouse and human) Full SOP · 7 phases · QC included
Disease modelling
LV-DS-16 Full SOP with Academic or a plan
RETINA
Publication-derived

Retinal Organoids for Developmental Studies under Hypoxia (RT-SC-23)

Source Du et al., 2023 · Senior Department of Ophthalmology, the Third Medical Center of Chinese PLA General Hospital, Beijing · DOI

Duration: 52 days Cell source: Human iPSC Full SOP · 4 phases · QC included
Developmental biology
RT-SC-23 Full SOP with Academic or a plan
BRAIN
Publication-derived

Microcephaly Cerebral Organoids for Infection Studies (BN-DS-16)

Source Dang et al., 2016 · University of California San Diego · DOI

Duration: 30 days Cell source: Human ESC (H9 hESCs) Full SOP · 11 phases · QC included
Disease modelling
BN-DS-16 Full SOP with Academic or a plan
BRAIN
Publication-derived

Brain Organoids for Disease Modelling with Interneurons (BN-DS-23)

Source Lu et al., 2023 · Institute for Stem Cell and Neural Regeneration, State Key Laboratory of Reproductive Medicine, School of Pharmacy, Nanjing Medical University · DOI

Duration: 70 days Cell source: Patient-Derived iPSC (Major Depressive Disorder with Suicide Behavior) Full SOP · 14 phases · QC included
Disease modelling
BN-DS-23 Full SOP with Academic or a plan
INTESTINAL
Publication-derived

Small Intestinal 2D Cell Cultures for Infection Studies (IN-DS-17)

Source Noel et al., 2017 · Johns Hopkins University School of Medicine; University of Maryland School of Medicine · DOI

Duration: 21 days Cell source: Human iPSC-derived enteroids; Human monocyte-derived macrophages Full SOP · 5 phases · QC included
Disease modelling
IN-DS-17 Full SOP with Academic or a plan
BRAIN
Publication-derived

Miller-Dieker Syndrome Cortical Organoids

Source Iefremova et al.

Duration: 33 days Cell source: Patient-Derived iPSC (Miller-Dieker Syndrome) Full SOP · 11 phases · QC included
Disease modelling
Full SOP with Academic or a plan
SKIN
Publication-derived

Skin Organoids for Disease Modelling (SK-DS-22)

Source Ramovs et al., 2022 · Leiden University Medical Center, Department of Anatomy and Embryology · DOI

Duration: 130 days Cell source: Human iPSC (LUMCi045-A1, LUMCi046-A1, WT2) Full SOP · 12 phases · QC included
Disease modelling
SK-DS-22 Full SOP with Academic or a plan
BRAIN
Publication-derived

Alzheimer's Disease Brain Organoids with Microglia (BN-DS-17)

Source Abud et al., 2017 · University of California Irvine · DOI

Duration: 38 days Cell source: Human iPSC Full SOP · 5 phases · QC included
Disease modelling
BN-DS-17 Full SOP with Academic or a plan
BRAIN
Publication-derived

Alzheimer's Disease Cerebral Organoids for Neuroinflammation Studies

Source Park et al. · Department of Biochemistry & Biomedical Sciences, Seoul National University College of Medicine · DOI

Duration: 65 days Cell source: Human iPSC, Patient-Derived iPSC (Alzheimer's Disease) Full SOP · 10 phases · QC included
Drug screening
Full SOP with Academic or a plan
INTESTINAL
Publication-derived

Colorectal Cancer Colonic Tumouroids for Transplantation (IN-CA-17)

Source Schütte et al., 2017 · Max Planck Institute for Molecular Genetics and Bayer AG · DOI

Duration: 90 days Cell source: Patient-Derived CRC (Primary tumours and metastases, stages I-IV) Full SOP · 14 phases · QC included
Drug screening
IN-CA-17 Full SOP with Academic or a plan
RETINA
Publication-derived

Retinal Organoids for Disease Modelling (2021) (RT-DS-21)

Source Isla-Magrané et al., 2021 · Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus · DOI

Duration: 140 days Cell source: Human iPSC Full SOP · 8 phases · QC included
Disease modelling
RT-DS-21 Full SOP with Academic or a plan
BRAIN
Publication-derived

Frontotemporal Lobar Degeneration with Tau Brain Organoids (BN-DS-25)

Source Ingram et al., 2025 · Department of Neuroscience, College of Medicine, The Ohio State University · DOI

Duration: 120 days Cell source: Patient-Derived iPSC (MAPT R406W mutation) Full SOP · 12 phases · QC included
Disease modelling
BN-DS-25 Full SOP with Academic or a plan
BRAIN
Publication-derived

Congenital Cytomegalovirus Infection Cortical Organoids (BN-DS-19)

Source Sison et al., 2019 · Medical College of Wisconsin · DOI

Duration: 60 days Cell source: Human iPSC Full SOP · 8 phases · QC included
Disease modelling
BN-DS-19 Full SOP with Academic or a plan
BRAIN
Publication-derived

Zika Virus Infection-Induced Microcephaly Brain Organoids (BN-DS-19)

Source Liu et al., 2019 · Brain and Spinal Cord Innovative Research Center, Tongji Hospital, Tongji University School of Medicine, Shanghai · DOI

Duration: 45 days Cell source: Human ESC (H9) Full SOP · 12 phases · QC included
Disease modelling
BN-DS-19 Full SOP with Academic or a plan
BRAIN
Publication-derived

Autism Spectrum Disorder Brain Organoids (BN-DS-17)

Source Wang et al., 2017 · Albert Einstein College of Medicine · DOI

Duration: 50 days Cell source: Human iPSC Full SOP · 12 phases · QC included
Disease modelling
BN-DS-17 Full SOP with Academic or a plan
RETINA
Publication-derived

Retinal Organoids for Drug Screening and Disease Modelling (RT-DS-21)

Source Wagstaff et al., 2021 · Department of Clinical Genetics, Amsterdam UMC, University of Amsterdam · DOI

Duration: 160 days Cell source: Human ESC (H1, WiCell) Full SOP · 8 phases · QC included
Drug screening
RT-DS-21 Full SOP with Academic or a plan
BRAIN
Publication-derived

Alzheimer's Disease Cerebral Organoids (2022) (BN-DS-22)

Source Hernández et al., 2022 · The University of Melbourne · DOI

Duration: 270 days Cell source: Human iPSC (reprogrammed from skin fibroblasts) Full SOP · 8 phases · QC included
Disease modelling
BN-DS-22 Full SOP with Academic or a plan
BRAIN
Publication-derived

Rett Syndrome Brain Organoids with Electrophysiology (BN-DS-21)

Source Samarasinghe et al., 2021 · David Geffen School of Medicine at UCLA · DOI

Duration: 107 days Cell source: Human iPSC (Rett syndrome patient-derived), Human ESC (H9) Full SOP · 7 phases · QC included
Drug screening
BN-DS-21 Full SOP with Academic or a plan
BRAIN
Publication-derived

Tauopathy Brain Assembloids (BN-DS-22)

Source Rickner et al., 2022 · Boston University · DOI

Duration: 21 days Cell source: Human iPSC Full SOP · 5 phases · QC included
Disease modelling
BN-DS-22 Full SOP with Academic or a plan
BRAIN
Publication-derived

22q11.2 Deletion Syndrome with Schizophrenia Brain Organoids (BN-DS-25)

Source Rao et al., 2025 · Mortimer B. Zuckerman Mind Brain and Behavior Institute, Columbia University · DOI

Duration: 150 days Cell source: Patient-Derived iPSC (22q11.2 deletion syndrome with schizophrenia) Full SOP · 10 phases · QC included
Disease modelling
BN-DS-25 Full SOP with Academic or a plan
LUNG
Publication-derived

Airway Organoids for Infection Studies (AW-DS-18)

Source Zhou et al., 2018 · The University of Hong Kong · DOI

Duration: 72 days Cell source: Human ASC-derived airway organoids from normal lung tissue Full SOP · 9 phases · QC included
Disease modelling
AW-DS-18 Full SOP with Academic or a plan
RETINA
Publication-derived

Retinal 2D Cell Cultures for Developmental Studies (2012) (RT-SC-12)

Source Phillips et al., 2012 · Waisman Center, University of Wisconsin-Madison · DOI

Duration: 108 days Cell source: Human iPSC (Blood-derived T lymphocytes) Full SOP · 7 phases · QC included
Developmental biology
RT-SC-12 Full SOP with Academic or a plan
BRAIN
Publication-derived

Miller-Dieker Syndrome Cortical Organoids for Disease Modelling (BN-DS-17)

Source Iefremova et al., 2017 · Institute of Reconstructive Neurobiology, University of Bonn · DOI

Duration: 35 days Cell source: Patient-Derived iPSC (Miller-Dieker Syndrome) Full SOP · 3 phases · QC included
Disease modelling
BN-DS-17 Full SOP with Academic or a plan