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934 protocols found
934 protocols found
BRAIN
Publication-derived

Parkinson's Disease Midbrain Organoids (2021, No. 2) (BN-DS-21)

Source Mohamed et al., 2021 · Montreal Neurological Institute-Hospital, McGill University · DOI

Duration: 170 days Cell source: Patient-Derived iPSC (SNCA triplication), CRISPR-corrected isogenic control iPSC Full SOP · 11 phases · QC included
Disease modelling
BN-DS-21 Full SOP with Academic or a plan
BREAST
Publication-derived

Breast Cancer Organoids with Gene Editing (BR-CA-20)

Source Dekkers et al., 2020 · The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia · DOI

Duration: 20 days Cell source: Human breast epithelial cells from reduction mammoplasties Full SOP · 10 phases · QC included
Drug screening
BR-CA-20 Full SOP with Academic or a plan
CARDIAC
Publication-derived

Cardiac Spheroids for Drug Screening and Regeneration (CD-DS-23)

Source Moriwaki et al., 2023 · Department of Cardiology, Keio University School of Medicine · DOI

Duration: 10 days Cell source: Human iPSC Full SOP · 10 phases · QC included
Drug screening
CD-DS-23 Full SOP with Academic or a plan
BRAIN
Publication-derived

Brain Tumour Cerebral Organoids (BN-CA-25)

Source Schickel et al., 2025 · GSI Helmholtzzentrum für Schwerionenforschung GmbH · DOI

Duration: 150 days Cell source: Human ESC (H9/WA09-FI) Full SOP · 6 phases · QC included
Disease modelling
BN-CA-25 Full SOP with Academic or a plan
LIVER
Publication-derived

Liver Organoids for Infection Studies (LV-DS-21)

Source Collett et al., 2021 · RMIT University, School of Science · DOI

Duration: 30 days Cell source: Human hepatocarcinoma cell line (Huh7) Full SOP · 10 phases · QC included
Disease modelling
LV-DS-21 Full SOP with Academic or a plan
BRAIN
Publication-derived

Glioblastoma Brain Organoids for Disease Modelling (BN-DS-24)

Source Fan et al., 2024 · Fudan University, Shanghai, China · DOI

Duration: 105 days Cell source: Human ESC (H9) and Patient-Derived GSC (Glioblastoma Stem Cell 3264) Full SOP · 10 phases · QC included
Disease modelling
BN-DS-24 Full SOP with Academic or a plan
BRAIN
Publication-derived

Alzheimer's Disease Cerebral Organoids for Developmental Studies (BN-DS-18)

Source Pavoni et al., 2018 · Service d'Etude des Prions et Infections Atypiques (SEPIA), Institut François Jacob, CEA, Université Paris-Saclay, Fontenay-aux-Roses, France · DOI

Duration: 5 days Cell source: Human iPSC Full SOP · 11 phases · QC included
Disease modelling
BN-DS-18 Full SOP with Academic or a plan
BRAIN
Publication-derived

Fetal Alcohol Spectrum Disorder Cerebral Organoids (BN-DS-20)

Source Arzua et al., 2020 · Medical College of Wisconsin · DOI

Duration: 61 days Cell source: Human iPSC Full SOP · 13 phases · QC included
Disease modelling
BN-DS-20 Full SOP with Academic or a plan
BRAIN
Publication-derived

Leigh Syndrome Brain Organoids

Source Romero-Morales et al. · Vanderbilt University · DOI

Duration: 365 days Cell source: Patient-Derived iPSC (Leigh Syndrome) Full SOP · 12 phases · QC included
Disease modelling
Full SOP with Academic or a plan
LIVER
Publication-derived

Liver Organoids for Drug Screening and Disease Modelling (LV-DS-19)

Source Mun et al., 2019 · Korea Research Institute of Bioscience and Biotechnology (KRIBB) · DOI

Duration: 25 days Cell source: Human iPSC, Human ESC Full SOP · 6 phases · QC included
Drug screening
LV-DS-19 Full SOP with Academic or a plan
BLADDER
Publication-derived

Bladder Cancer Tumouroids

Source Lee et al., 2018 · Columbia University Medical Center · DOI

Duration: 14 days Cell source: Patient-Derived Urothelial Carcinoma (mixed: non-muscle invasive and muscle invasive bladder cancer) Full SOP · 8 phases · QC included
Drug screening
Full SOP with Academic or a plan
LIVER
Publication-derived

Liver Organoids for Regenerative Medicine with Stromal Cells (LV-SC-21)

Source Nigro et al., 2021 · Mediterranean Institute for Transplantation and Advanced Specialized Therapies (IRCCS ISMETT), Palermo, Italy · DOI

Duration: 22 days Cell source: Human EpCAM+ liver progenitor cells (primary) + Human amnion-derived mesenchymal stromal/stem cells (hAMSCs) Full SOP · 11 phases · QC included
Regenerative medicine
LV-SC-21 Full SOP with Academic or a plan
LUNG
Publication-derived

Lung Organoids for Infection and Disease Modelling (AW-FI-17)

Source Chen et al., 2017 · Columbia University Medical Center · DOI

Duration: 210 days Cell source: Human ESC (RUES2) and Human iPSC Full SOP · 14 phases · QC included
Disease modelling
AW-FI-17 Full SOP with Academic or a plan
BRAIN
Publication-derived

SARS-CoV-2 Neuropathology Brain Assembloids (BN-DS-21)

Source Wang et al., 2021 · University of California San Diego · DOI

Duration: 74 days Cell source: Human iPSC-derived neural crest stem cells (NCSCs), H1-hESC Full SOP · 6 phases · QC included
Disease modelling
BN-DS-21 Full SOP with Academic or a plan
BRAIN
Publication-derived

Meningioma Brain Organoids

Source Jungwirth et al. · Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University · DOI

Duration: 45 days Cell source: Patient-Derived Meningioma Tissue Full SOP · 11 phases · QC included
Drug screening
Full SOP with Academic or a plan
ENDOMETRIUM
Publication-derived

Endometrial Organoids for Drug Screening (EM-DS-17)

Source Boretto et al., 2017 · KU Leuven (University of Leuven) · DOI

Duration: 25 days Cell source: Human endometrial tissue (from biopsies) Full SOP · 6 phases · QC included
Drug screening
EM-DS-17 Full SOP with Academic or a plan
BRAIN
Publication-derived

Herpes Simplex Virus Infection Brain Organoids (BN-DS-21)

Source Krenn et al., 2021 · Institute of Molecular Biotechnology (IMBA), Vienna BioCenter (VBC), Vienna, Austria · DOI

Duration: 65 days Cell source: Human ESC (H9) Full SOP · 11 phases · QC included
Disease modelling
BN-DS-21 Full SOP with Academic or a plan
BRAIN
Publication-derived

Frontotemporal Dementia Cerebral Organoids (BN-DS-22)

Source Glasauer et al., 2022 · University of California, Santa Barbara, Neuroscience Research Institute · DOI

Duration: 96 days Cell source: Human iPSC from MAPT mutation carriers and isogenic controls Full SOP · 7 phases · QC included
Disease modelling
BN-DS-22 Full SOP with Academic or a plan
BRAIN
Publication-derived

Parkinson's Disease Midbrain Organoids with Astrocytes (BN-DS-20)

Source Kano et al., 2020 · Juntendo University Graduate School of Medicine · DOI

Duration: 35 days Cell source: Patient-Derived iPSC (Parkinson's disease - PRKN mutations) Full SOP · 6 phases · QC included
Disease modelling
BN-DS-20 Full SOP with Academic or a plan
LIVER
Publication-derived

Fatty Liver Disease Organoids (LV-DS-25)

Source Qin et al., 2025 · Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, the Second Affiliated Hospital, School of Medicine, South China University of Technology · DOI

Duration: 15 days Cell source: Human ESC (H9 line) Full SOP · 7 phases · QC included
Drug screening
LV-DS-25 Full SOP with Academic or a plan
BRAIN
Publication-derived

Parkinson's Disease Midbrain Organoids for Developmental Studies (BN-DS-22)

Source Lee et al., 2022 · Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, South Korea · DOI

Duration: 30 days Cell source: Human ESC (H9) and Human iPSC (LRRK2 G2019S mutant and gene-corrected) Full SOP · 5 phases · QC included
Disease modelling
BN-DS-22 Full SOP with Academic or a plan
BRAIN
Publication-derived

Familial Bipolar Disorder Cortical Organoids (BN-DS-24)

Source Phalnikar et al., 2024 · Institute for Stem Cell Science and Regenerative Medicine (inStem), Bengaluru, India · DOI

Duration: 50 days Cell source: Patient-Derived iPSC (Familial Bipolar Disorder) Full SOP · 10 phases · QC included
Disease modelling
BN-DS-24 Full SOP with Academic or a plan
RETINA
Publication-derived

Retinal Organoids for Disease and Development (RT-DS-18)

Source Felemban et al., 2018 · Institute of Genetic Medicine, Newcastle University, UK · DOI

Duration: 164 days Cell source: Human ESC (H9), Human iPSC (SB-Ad3) Full SOP · 7 phases · QC included
Disease modelling
RT-DS-18 Full SOP with Academic or a plan
LIVER
Publication-derived

Hepatoblastoma Liver Organoids (LV-DS-25)

Source Balaseviciute et al., 2025 · Mount Sinai Liver Cancer Program, Icahn School of Medicine at Mount Sinai; Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Hospital Clínic, Universitat de Barcelona · DOI

Duration: 28 days Cell source: Patient-Derived xenograft (PDX) HB tumors; PDX-derived cell lines (TT001); HepG2 cell line; Patient-derived organoids from CTNNB1-mutant HB Full SOP · 6 phases · QC included
Drug screening
LV-DS-25 Full SOP with Academic or a plan