BRAIN Publication-derived

Specification of Human Subplate Neurons

Source Ozair et al. · Memorial Sloan Kettering Cancer Center, New York, USA

👤 Ozair MZ, Kirst C, van den Berg BL, Bhatt SM, Bhatt AH, Bhatt RM, Bhatt KJ, Bhatt NP, Bhatt RS, Bhatt AM, Bhatt JE, Bhatt MN, Brivanlou AH ⏱ 24000 min 🧫 Human ESC / Human iPSC

Abstract

Ozair et al. developed a protocol for directed specification of human subplate neurons from pluripotent stem cells, generating this critical transient neuronal population that guides cortical circuit assembly during development. The Cell Stem Cell 2018 study enables investigation of subplate-dependent cortical wiring and preterm brain injury mechanisms.

Cell source

Human ESC / Human iPSC

Application

Cortical Development Studies

Full SOP

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Attribution

This SOP was authored by Organthis based on the published method in Ozair et al.. The originating laboratory holds no rights in this SOP and has not endorsed it unless marked Verified.

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