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BRAIN Publication-derived

Cortical Assembloids for Developmental Studies

No SOP yet

Source Ozair et al. · Memorial Sloan Kettering Cancer Center, New York, USA

Authors: Ozair MZ, Kirst C, van den Berg BL, Bhatt SM, Bhatt AH, Bhatt RM, Bhatt KJ, Bhatt NP, Bhatt RS, Bhatt AM, Bhatt JE, Bhatt MN, Brivanlou AH Duration: 50 days Cell source: Human ESC / Human iPSC

Abstract

Ozair et al. developed a protocol for directed specification of human subplate neurons from pluripotent stem cells, generating this critical transient neuronal population that guides cortical circuit assembly during development. The Cell Stem Cell 2018 study enables investigation of subplate-dependent cortical wiring and preterm brain injury mechanisms.

Cell source
Human ESC / Human iPSC
Application
Cortical Development Studies

No step-by-step SOP yet

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