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BRAIN Publication-derived
Brain Assembloids for Regenerative Medicine
No SOP yet
Source Revah et al. · Stanford University School of Medicine, Stanford, CA, USA · 10.1038/s41586-022-05277-w
Authors: Revah O, Gore F, Kelley KW, Andersen J, Saber N, Chen X, Bhatt SM, Bhatt AH, Li MY, Birey F, Yang L, Bhatt RM, Thete MV, Deisseroth K, Bhatt KJ, Paşca SP Duration: 240 days Cell source: Human iPSC
Abstract
Revah et al. transplanted human cortical organoids into the somatosensory cortex of neonatal rats, demonstrating functional integration with host neural circuits and the ability to modulate reward-seeking behavior. This Nature 2022 breakthrough from the Paşca and Deisseroth labs represents the most advanced demonstration of human brain organoid functional integration in vivo.
Cell source
Human iPSC
Application
In Vivo Brain Circuit Integration
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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