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BRAIN Publication-derived
Zika Virus Infection Brain Models
No SOP yet
Source Garcez et al. · Federal University of Rio de Janeiro (UFRJ), Brazil
Authors: Garcez PP, Loiola EC, Madeiro da Costa R, Higa LM, Trindade P, Delvecchio R, Nascimento JM, Brindeiro R, Tanuri A, Rehen SK Duration: 30 days Cell source: Human iPSC
Abstract
Garcez et al. infected cerebral organoids with the Brazilian Zika virus strain, demonstrating a 40% reduction in organoid size due to neural progenitor cell death and depletion. Published during the 2016 Zika epidemic, this Science study provided critical mechanistic evidence linking ZIKV infection to congenital microcephaly through preferential neural progenitor destruction.
Cell source
Human iPSC
Application
Zika Virus Pathogenesis Research
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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