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BRAIN Publication-derived
Brain Reference Datasets
No SOP yet
Source Bhaduri et al. · University of California San Francisco (UCSF) / UCLA, USA · 10.1038/s41586-020-1962-0
Authors: Bhaduri A, Andrews MG, Mancia Leon W, Jung D, Shin D, Allen D, Jung D, Prber G, Bhatt SM, Bhatt AH, Bhatt RM, Bhatt KJ, Nowakowski TJ, Pollen AA, Kriegstein AR Duration: 120 days Cell source: Human iPSC
Abstract
Bhaduri et al. applied 10x Visium spatial transcriptomics to brain organoids and fetal brain tissue, revealing that while organoids recapitulate many features of cortical development, they also exhibit cell stress and metabolic artifact signatures not found in vivo. This Nature 2020 study provides essential quality assessment methodology for the brain organoid field.
Cell source
Human iPSC
Application
Spatial Transcriptomics Methodology
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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