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BRAIN Publication-derived

Self-Forming Optic Cup from Human ESCs

Source Nakano et al. · RIKEN Center for Developmental Biology, Kobe, Japan

👤 Nakano T, Ando S, Takata N, Kawada M, Muguruma K, Sekiguchi K, Saito K, Yonemura S, Eiraku M, Sasai Y ⏱ 28800 min 🧫 Human ESC

Abstract

Nakano et al. demonstrated the first self-organizing optic cup formation from human ESCs using the SFEBq method with WNT inhibition, recapitulating the morphogenetic invagination that generates the bilayered optic cup in vivo. This landmark RIKEN/Sasai lab publication established the foundation for all subsequent retinal organoid research.

Cell source
Human ESC
Application
Retinal Development Studies

Full SOP

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Attribution

This SOP was authored by Organthis based on the published method in Nakano et al.. The originating laboratory holds no rights in this SOP and has not endorsed it unless marked Verified.

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