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BRAIN Publication-derived
Retinitis Pigmentosa Retinal Organoids
No SOP yet
Source Deng et al. · Wenzhou Medical University / National Eye Institute (NEI), China / USA · 10.1016/j.stemcr.2018.02.010
Authors: Deng WL, Gao ML, Lei XL, Lv JN, Zhao H, He KW, Xia XX, Li LY, Chen YC, Li YP, Pan D, Xue T, Jin ZB Duration: 150 days Cell source: Patient-Derived iPSC (Retinitis Pigmentosa)
Abstract
Deng et al. established patient-derived iPSC retinal organoids from individuals with retinitis pigmentosa as a preclinical platform for screening AAV gene therapy vectors, demonstrating successful photoreceptor transduction and functional rescue of the RP phenotype.
Cell source
Patient-Derived iPSC (Retinitis Pigmentosa)
Application
Retinitis Pigmentosa Gene Therapy Development
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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