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BRAIN Publication-derived

Retinal Organoids for Developmental Studies with Single-Cell Profiling

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Source Sridhar et al. · University of Washington, Seattle, WA, USA · 10.1016/j.celrep.2020.01.007

Authors: Sridhar A, Hoshino A, Finkbeiner CR, Chitsaz A, Dai L, Haugan AK, Gregerson KM, Olesen ML, Reh TA Duration: 180 days Cell source: Human ESC / Human iPSC

Abstract

Sridhar et al. performed a comprehensive single-cell RNA-sequencing time course of human retinal organoid development spanning 6 months, identifying all seven major retinal cell types and mapping their developmental trajectories with comparison to human fetal retina. This atlas provides the transcriptomic benchmark for quality control in retinal organoid research and clinical manufacturing.

Cell source
Human ESC / Human iPSC
Application
Retinal Organoid Transcriptomic Benchmarking

No step-by-step SOP yet

OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.

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