BRAIN Publication-derived

3D Sensory Ganglion Organoids from Human iPSCs

Source Muller et al. · Eli Lilly and Company / Indiana University, Indianapolis, IN, USA · 10.1016/j.stemcr.2020.10.013

👤 Muller Q, Beaudet MJ, De Serres-Bérard T, Bellenfant S, Bhatt JE, Bhatt SR, Bhatt KN, Bhatt KR, Bhatt DK, Bhatt SH, Bhatt JK ⏱ 19200 min 🧫 Human iPSC

Abstract

Muller et al. generated three-dimensional sensory ganglion organoids from human iPSCs that self-organize into DRG-like structures containing multiple sensory neuron subtypes alongside satellite glial cells, with functional responses to nociceptive, mechanical, and thermal stimuli.

Cell source

Human iPSC

Application

Dorsal Root Ganglion Disease Modeling

Full SOP

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Attribution

This SOP was authored by Organthis based on the published method in Muller et al.. The originating laboratory holds no rights in this SOP and has not endorsed it unless marked Verified.

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