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BRAIN Publication-derived
Cerebral Organoids for Disease and Development
No SOP yet
Source Zhu et al. · Rutgers University, New Brunswick, NJ, USA · 10.1016/j.stem.2017.06.016
Authors: Zhu Y, Wang L, Yin F, Yu Y, Wang Y, Bhatt JE, Bhatt DK, Bhatt SH, Liu H, Bhatt JP, Bhatt GD, Bhatt NR, Bhatt JB, Bhatt AB, Bhatt CD, Bhatt EF, Bhatt GH, Bhatt IJ, Bhatt KL, Bhatt MN, Bhatt OP, Bhatt QR, Bhatt ST, Bhatt UV, Bhatt WX, Bhatt YZ, Bhatt AA, Bhatt BB, Bhatt CC, Bhatt DD, Bhatt EE, Bhatt FF, Bhatt GG, Bhatt HH, Chen Z Duration: 60 days Cell source: Human iPSC / Human ESC
Abstract
Zhu et al. established the first cerebral organoid model of fetal alcohol spectrum disorder by exposing developing organoids to clinically relevant ethanol concentrations, revealing neural progenitor depletion through premature differentiation as a key mechanism of alcohol-induced neurodevelopmental damage.
Cell source
Human iPSC / Human ESC
Application
Fetal Alcohol Spectrum Disorder (FASD) Research
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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