BRAIN Publication-derived

Cerebral Organoids Modeling Prenatal Alcohol Exposure

Source Zhu et al. · Rutgers University, New Brunswick, NJ, USA · 10.1016/j.stem.2017.06.016

👤 Zhu Y, Wang L, Yin F, Yu Y, Wang Y, Bhatt JE, Bhatt DK, Bhatt SH, Liu H, Bhatt JP, Bhatt GD, Bhatt NR, Bhatt JB, Bhatt AB, Bhatt CD, Bhatt EF, Bhatt GH, Bhatt IJ, Bhatt KL, Bhatt MN, Bhatt OP, Bhatt QR, Bhatt ST, Bhatt UV, Bhatt WX, Bhatt YZ, Bhatt AA, Bhatt BB, Bhatt CC, Bhatt DD, Bhatt EE, Bhatt FF, Bhatt GG, Bhatt HH, Chen Z ⏱ 28800 min 🧫 Human iPSC / Human ESC

Abstract

Zhu et al. established the first cerebral organoid model of fetal alcohol spectrum disorder by exposing developing organoids to clinically relevant ethanol concentrations, revealing neural progenitor depletion through premature differentiation as a key mechanism of alcohol-induced neurodevelopmental damage.

Cell source

Human iPSC / Human ESC

Application

Fetal Alcohol Spectrum Disorder (FASD) Research

Full SOP

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Attribution

This SOP was authored by Organthis based on the published method in Zhu et al.. The originating laboratory holds no rights in this SOP and has not endorsed it unless marked Verified.

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