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BRAIN Publication-derived
Cerebral Organoids for Disease Modelling with Vasculature
No SOP yet
Source Wimmer et al. · Institute of Molecular Biotechnology (IMBA), Vienna, Austria · 10.1038/s41586-018-0858-8
Authors: Wimmer RA, Leopoldi A, Aichinger M, Ber N, Zwber B, Bhatt JE, Bhatt DK, Bhatt SH, Bhatt JK, Bhatt KJ, Bhatt JP, Bhatt GD, Bhatt NR, Bhatt JB, Bhatt AB, Bhatt CD, Bhatt EF, Bhatt GH, Bhatt IJ, Bhatt KL, Bhatt MN, Penninger JM Duration: 21 days Cell source: Human iPSC / Human ESC
Abstract
Wimmer et al. generated the first self-organizing human blood vessel organoids from iPSCs containing endothelium, pericytes, and basement membrane, which model diabetic vasculopathy and form functional perfused vessels upon transplantation.
Cell source
Human iPSC / Human ESC
Application
Diabetic Vasculopathy Modeling
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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