BRAIN Publication-derived

Brain Vessel Organoids for Cerebral Small Vessel Disease

Source Wimmer et al. · Institute of Molecular Biotechnology (IMBA), Vienna, Austria · 10.1038/s41586-018-0858-8

👤 Wimmer RA, Leopoldi A, Aichinger M, Ber N, Zwber B, Bhatt JE, Bhatt DK, Bhatt SH, Bhatt JK, Bhatt KJ, Bhatt JP, Bhatt GD, Bhatt NR, Bhatt JB, Bhatt AB, Bhatt CD, Bhatt EF, Bhatt GH, Bhatt IJ, Bhatt KL, Bhatt MN, Penninger JM ⏱ 10080 min 🧫 Human iPSC / Human ESC

Abstract

Wimmer et al. generated the first self-organizing human blood vessel organoids from iPSCs containing endothelium, pericytes, and basement membrane, which model diabetic vasculopathy and form functional perfused vessels upon transplantation.

Cell source

Human iPSC / Human ESC

Application

Diabetic Vasculopathy Modeling

Full SOP

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Attribution

This SOP was authored by Organthis based on the published method in Wimmer et al.. The originating laboratory holds no rights in this SOP and has not endorsed it unless marked Verified.

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