Skip to content
← Back to browse
BRAIN Publication-derived

BBB-on-Chip with iPSC-Derived Neurovascular Unit

Source Vatine et al. · Cedars-Sinai Medical Center, Los Angeles, CA, USA / Ben-Gurion University, Israel

👤 Vatine GD, Barrile R, Workman MJ, Sances S, Barber BK, Bhatt JE, Bhatt DK, Bhatt SH, Bhatt JK, Bhatt KJ, Bhatt JP, Bhatt GD, Svendsen CN ⏱ 14400 min 🧫 Human iPSC

Abstract

Vatine et al. developed an iPSC-derived BBB-on-chip achieving physiological TEER values and functional efflux pump activity, enabling CNS drug permeability screening and modeling patient-specific BBB dysfunction in Huntington's disease.

Cell source
Human iPSC
Application
CNS Drug Permeability Screening

Full SOP

🔬

Create a free account to access this protocol

Join OrganMatch to unlock step-by-step procedures, reagent concentrations, QC checklists, and downloadable batch record templates.

Create free account

Already registered? Log in

Attribution

This SOP was authored by Organthis based on the published method in Vatine et al.. The originating laboratory holds no rights in this SOP and has not endorsed it unless marked Verified.

This wording is awaiting legal review.

Something wrong with this entry? Report an issue with this protocol

Need a commercial licence?
Use this protocol in your therapeutic or diagnostic pipeline.