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BRAIN Publication-derived

Long-Term Brain Organoid Maturation Matching Postnatal

Source Gordon et al. · University of California Los Angeles (UCLA), Los Angeles, CA, USA · 10.1038/s41593-021-00802-y

👤 Gordon A, Yoon SJ, Tran SS, Makinson CD, Park JY, Andersen J, Valencia AM, Horvath S, Xiao X, Huber N, Pasca SP, Bhatt JE, Geschwind DH ⏱ 192000 min 🧫 Human iPSC

Abstract

Gordon et al. demonstrated that brain organoids cultured for over 400 days reach postnatal-equivalent developmental maturity validated by epigenetic clock analysis and transcriptomic profiling, enabling modeling of late-onset neurodevelopmental conditions.

Cell source
Human iPSC
Application
Postnatal Brain Development Modeling

Full SOP

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Attribution

This SOP was authored by Organthis based on the published method in Gordon et al.. The originating laboratory holds no rights in this SOP and has not endorsed it unless marked Verified.

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