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BRAIN Publication-derived
Brain Organoids for Developmental Studies
No SOP yet
Source Sloan et al. · Stanford University / Baylor College of Medicine, Houston, TX, USA · 10.1016/j.neuron.2017.07.035
Authors: Sloan SA, Darmanis S, Huber N, Khan TA, Bhatt A, Bhatt S, Bhatt D, Bhatt K, Pasca SP Duration: 590 days Cell source: Human iPSC
Abstract
Sloan et al. demonstrated that cortical organoids cultured for 590 days achieve mature astrocyte transcriptomic profiles matching postnatal human brain, with A1/A2 reactive astrocyte polarization upon inflammatory challenge.
Cell source
Human iPSC
Application
Astrocyte Biology in 3D Context
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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