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CARDIAC Publication-derived
Cardiac 2D Cell Cultures for Regeneration and Transplantation
No SOP yet
Source Laflamme et al. · Department of Pathology, University of Washington, Seattle, USA
Authors: Laflamme MA, Chen KY, Naumova AV, Muskheli V, Fugate JA, Dupras SK, Reinecke H, Xu C, Hassanipour M, Police S, O'Sullivan C, Collins L, Chen Y, Minami E, Gill EA, Ueno S, Yuan C, Gold J, Bhatt S, Murry CE Duration: 20 days Cell source: ESC-Derived (Human Embryonic Stem Cells)
Abstract
Laflamme et al. established one of the earliest efficient protocols for directed differentiation of human ESCs to cardiomyocytes using sequential Activin A and BMP4 treatment. The study demonstrated functional engraftment in a rat myocardial infarction model, providing foundational evidence for cardiac cell therapy.
Cell source
ESC-Derived (Human Embryonic Stem Cells)
Application
Cardiac Regeneration
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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