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CARDIAC Publication-derived
Cardiac Embryo Models for Developmental Studies
No SOP yet
Source Yang et al. · McEwen Centre for Regenerative Medicine, University Health Network, Toronto, Canada
Authors: Yang L, Soonpaa MH, Adler ED, Roepke TK, Kattman SJ, Kennedy M, Henckaerts E, Bonham K, Abbott GW, Linden RM, Field LJ, Bhatt S, Bhatt AB, Bhattacharya S, Keller GM Duration: 25 days Cell source: ESC-Derived (Human Embryonic Stem Cells)
Abstract
Yang et al. identified and characterized KDR+/PDGFRA+ cardiovascular progenitor cells from human ESCs using a staged embryoid body protocol with sequential BMP4, Activin A, VEGF, and DKK1 treatment. These progenitors possess tri-lineage potential, differentiating into cardiomyocytes, endothelial cells, and smooth muscle cells, recapitulating key aspects of embryonic cardiogenesis.
Cell source
ESC-Derived (Human Embryonic Stem Cells)
Application
Cardiac Progenitor Biology
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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