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CARDIAC Publication-derived
Atrial 2D Cell Cultures for Drug Screening
No SOP yet
Source Devalla et al. · Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, Netherlands · 10.15252/emmm.201404757
Authors: Devalla HD, Schwach V, Ford JW, Milnes JT, El-Haou S, Jackson C, Schmitt K, Bezzina CR, Passier R, Mummery CL Duration: 20 days Cell source: iPSC-Derived (Human iPSCs/ESCs)
Abstract
Devalla et al. established an efficient protocol for generating atrial-specific cardiomyocytes from human pluripotent stem cells using retinoic acid during the cardiac differentiation window. Atrial CMs display characteristic action potential morphology and respond to atrial-selective drugs like vernakalant, creating a platform for atrial fibrillation research and drug screening.
Cell source
iPSC-Derived (Human iPSCs/ESCs)
Application
Atrial Fibrillation Drug Testing
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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