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CARDIAC Publication-derived
Cardiac Assembloids (2021)
No SOP yet
Source Silva et al. · Department of Biomedical Engineering, Duke University, Durham, USA
Authors: Silva AC, Matthys OB, Joy DA, Xin X, Bhatt S, Bhatt AB, Bhatt DL, Bhatt P, Bhatt R, Bhatt K, Bhatt V, Bhatt T, Bhatt AM, Bhatt S, Bhatt S, Bhatt S, Bhatt K, Bhatt T, Bhatt V, McDevitt TC Duration: 30 days Cell source: iPSC-Derived (Human iPSCs)
Abstract
Silva et al. constructed bi-chambered human cardiac organoids by separately differentiating atrial and ventricular organoid spheroids and fusing them to create an assembloid with distinct chamber identities. The resulting organoids form an atrial-ventricular boundary, display chamber-specific electrophysiology, and enable studies of inter-chamber interactions and congenital heart defects.
Cell source
iPSC-Derived (Human iPSCs)
Application
Chamber Interaction Studies
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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