Throughput Screening (iPSC)
Source Giacomelli et al. · Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, Netherlands · 10.1016/j.stem.2020.05.004
Abstract
Giacomelli et al. developed tri-cell cardiac microtissues by self-assembly of iPSC-derived cardiomyocytes, endothelial cells, and cardiac fibroblasts. The multi-cell composition enhances cardiomyocyte maturation and drug sensitivity compared to monoculture, providing a scalable platform for high-throughput cardiotoxicity screening in standard multi-well formats.
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Attribution
This SOP was authored by Organthis based on the published method in Giacomelli et al.. The originating laboratory holds no rights in this SOP and has not endorsed it unless marked Verified.
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