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CARDIAC Publication-derived
Cardiac Bioprinted and Engineered Tissues for Drug Screening
No SOP yet
Source Zimmermann et al. · Institute of Pharmacology and Toxicology, University Medical Center Goettingen, Goettingen, Germany
Authors: Zimmermann WH, Schneiderbanger K, Schubert P, Didie M, Munzel F, Heubach JF, Kostin S, Neuhuber WL, Eschenhagen T Duration: 21 days Cell source: iPSC-Derived (Human iPSCs/ESCs)
Abstract
Zimmermann et al. established the ring-shaped engineered heart tissue (EHT) format using cardiomyocytes in collagen/Matrigel hydrogels under auxotonic mechanical loading. The EHTs develop aligned sarcomeres, generate measurable isometric force, and display Frank-Starling behavior, establishing the foundational technology for cardiac tissue engineering and drug testing.
Cell source
iPSC-Derived (Human iPSCs/ESCs)
Application
Cardiac Force Measurement
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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