CARDIAC Publication-derived

CMs

Source Zimmermann et al. · Institute of Pharmacology and Toxicology, University Medical Center Goettingen, Goettingen, Germany

👤 Zimmermann WH, Schneiderbanger K, Schubert P, Didie M, Munzel F, Heubach JF, Kostin S, Neuhuber WL, Eschenhagen T ⏱ 10080 min 🧫 iPSC-Derived (Human iPSCs/ESCs)

Abstract

Zimmermann et al. established the ring-shaped engineered heart tissue (EHT) format using cardiomyocytes in collagen/Matrigel hydrogels under auxotonic mechanical loading. The EHTs develop aligned sarcomeres, generate measurable isometric force, and display Frank-Starling behavior, establishing the foundational technology for cardiac tissue engineering and drug testing.

Cell source

iPSC-Derived (Human iPSCs/ESCs)

Application

Cardiac Force Measurement

Full SOP

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Attribution

This SOP was authored by Organthis based on the published method in Zimmermann et al.. The originating laboratory holds no rights in this SOP and has not endorsed it unless marked Verified.

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