Well Format for Drug Screening
Source Hansen et al. · Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Abstract
Hansen et al. miniaturized the EHT format into a 24-well fibrin-based system where cardiac tissues form between flexible PDMS posts. Video-optical tracking of post deflection provides automated, non-invasive force measurement, enabling medium-throughput drug screening validated with >20 reference compounds showing adult-like pharmacological responses.
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Attribution
This SOP was authored by Organthis based on the published method in Hansen et al.. The originating laboratory holds no rights in this SOP and has not endorsed it unless marked Verified.
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