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CARDIAC Publication-derived
Cardiac Bioprinted and Engineered Tissues for Drug Screening in Fibrin
No SOP yet
Source Hansen et al. · Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Authors: Hansen A, Eder A, Bonstrup M, Flber M, Pfeiffer S, Schloss S, Terber A, Schwoerer A, Bhatt S, Eschenhagen T Duration: 14 days Cell source: iPSC-Derived (Human iPSC-CMs)
Abstract
Hansen et al. miniaturized the EHT format into a 24-well fibrin-based system where cardiac tissues form between flexible PDMS posts. Video-optical tracking of post deflection provides automated, non-invasive force measurement, enabling medium-throughput drug screening validated with >20 reference compounds showing adult-like pharmacological responses.
Cell source
iPSC-Derived (Human iPSC-CMs)
Application
Medium-Throughput Drug Screening
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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