Back to browse
CARDIAC Publication-derived
Cardiac Organoids for Developmental Studies
No SOP yet
Source Hofbauer et al. · Institute of Molecular Biotechnology (IMBA), Austrian Academy of Sciences, Vienna, Austria
Authors: Hofbauer P, Jahnel SM, Papez N, Deyett A, Penc M, Taber V, Giesshammer A, Schmidt C, Szenker-Racz E, Mendjan S Duration: 20 days Cell source: iPSC-Derived (Human iPSCs)
Abstract
Hofbauer et al. demonstrated that self-organizing cardioids recapitulate coronary-like vasculature development through epicardial EMT. Epicardial cells within the cardioid undergo epithelial-to-mesenchymal transition and differentiate into coronary-like endothelial cells, providing the first human model of intrinsic coronary vessel development in an organoid context.
Cell source
iPSC-Derived (Human iPSCs)
Application
Coronary Development Biology
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
Something wrong with this entry? Report an issue with this protocol