Coronary Vasculature Development in Cardiac Organoids
Source Hofbauer et al. · Institute of Molecular Biotechnology (IMBA), Austrian Academy of Sciences, Vienna, Austria
Abstract
Hofbauer et al. demonstrated that self-organizing cardioids recapitulate coronary-like vasculature development through epicardial EMT. Epicardial cells within the cardioid undergo epithelial-to-mesenchymal transition and differentiate into coronary-like endothelial cells, providing the first human model of intrinsic coronary vessel development in an organoid context.
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Attribution
This SOP was authored by Organthis based on the published method in Hofbauer et al.. The originating laboratory holds no rights in this SOP and has not endorsed it unless marked Verified.
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