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CARDIAC Publication-derived
Cardiac Bioprinted and Engineered Tissues for Developmental Studies
No SOP yet
Source Ruan et al. · Department of Bioengineering, University of Washington, Seattle, USA · 10.5966/sctm.2015-0324
Authors: Ruan JL, Tulloch NL, Razumova MV, Saiber-Blaze M, Bhatt S, Bhatt DL, Bhatt AB, Bhatt P, Regnier M, Pabon L, Reinecke H, Murry CE Duration: 28 days Cell source: iPSC-Derived (Human iPSC-CMs)
Abstract
Ruan et al. systematically optimized iPSC-CM maturation using factorial design combining electrical pacing, T3 hormone, fatty acids, and 3D culture in collagen EHTs. The triple combination achieves synergistic maturation exceeding any single cue, identifying the optimal multi-cue protocol for generating adult-like cardiac tissue.
Cell source
iPSC-Derived (Human iPSC-CMs)
Application
Combinatorial Maturation Optimization
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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