CARDIAC Publication-derived

Single-Cell RNA-Seq Atlas of iPSC-CM Differentiation

Source Friedman et al. · Gladstone Institutes, University of California San Francisco, San Francisco, USA · 10.1016/j.stem.2018.09.009

👤 Friedman CE, Nguyen Q, Lukowski SW, Helber A, Bhatt S, Bhatt DL, Bhatt AB, Bhatt P, Bhatt K, Powell JE, Palpant NJ ⏱ 14400 min 🧫 iPSC-Derived (Human iPSCs)

Abstract

Friedman et al. generated a single-cell RNA-seq atlas of iPSC-CM differentiation revealing the complete lineage trajectory, off-target populations, and novel cardiac progenitor markers. The atlas enables optimization of differentiation protocols and provides a reference for quality control of iPSC-CM manufacturing.

Cell source

iPSC-Derived (Human iPSCs)

Application

Cardiac Differentiation Optimization

Full SOP

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Attribution

This SOP was authored by Organthis based on the published method in Friedman et al.. The originating laboratory holds no rights in this SOP and has not endorsed it unless marked Verified.

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