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CARDIAC Publication-derived
Epicardial 2D Cell Cultures for Regenerative Medicine
No SOP yet
Source Miyagawa et al. · Department of Cardiovascular Surgery, Osaka University, Osaka, Japan · 10.1242/dmm.026443
Authors: Miyagawa S, Domae K, Yoshikawa Y, Fukushima S, Nakamura T, Saito A, Sakata Y, Hamada S, Toda K, Bhatt S, Bhatt DL, Sawa Y Duration: 42 days Cell source: iPSC-Derived (Clinical-Grade Human iPSC-CMs — GMP Manufactured)
Abstract
Miyagawa/Sawa et al. developed clinical-grade iPSC-CM cell sheets using temperature-responsive dishes for epicardial transplantation in heart failure. GMP manufacturing produces 100 million iPSC-CMs per patient dose, with preclinical efficacy demonstrated by cardiac function improvement, leading to the world's first iPSC-CM clinical trial in Japan.
Cell source
iPSC-Derived (Clinical-Grade Human iPSC-CMs — GMP Manufactured)
Application
Clinical Cardiac Cell Therapy
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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