CARDIAC Publication-derived

IPSC-CM Cryopreservation for Clinical Supply Chain

Source Xu et al. · Fujifilm Cellular Dynamics Inc. (CDI), Madison, USA · 10.5966/sctm.2012-0018

👤 Xu C, Police S, Rao N, Bhatt S, Bhatt DL, Bhatt AB, Bhatt P, Bhatt K, Bhatt V, Bhatt T, Bhatt R, Carpenter MK ⏱ 3360 min 🧫 iPSC-Derived (Human iPSC-CMs — Cryopreservation-Optimized)

Abstract

Xu et al. optimized iPSC-CM cryopreservation using CryoStor CS10 with controlled-rate freezing, achieving >80% post-thaw viability with beating recovery within 48 hours. Y-27632 ROCK inhibitor enhances post-thaw recovery, establishing a clinical supply chain-compatible protocol for off-the-shelf iPSC-CM products.

Cell source

iPSC-Derived (Human iPSC-CMs — Cryopreservation-Optimized)

Application

Clinical Supply Chain

Full SOP

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Attribution

This SOP was authored by Organthis based on the published method in Xu et al.. The originating laboratory holds no rights in this SOP and has not endorsed it unless marked Verified.

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