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INTESTINAL Publication-derived
Intestinal Organoids for Drug Screening (2019)
No SOP yet
Source Ooft et al. · Princess Máxima Center and Hubrecht Institute, Utrecht, Netherlands
Authors: Ooft SN, Weeber F, Dijkstra KK, McLean CM, Lorber S, Maaskant JJ, Huitema S, Templeton A, Clevers H, Voest EE Duration: 45 days Cell source: Patient-Derived (CRC Tumor Biopsies, Multi-Center)
Abstract
Demonstrated that patient-derived CRC organoids can predict clinical response to irinotecan-based chemotherapy regimens in metastatic colorectal cancer. Prospective validation showed organoid drug sensitivity testing could be completed within clinical timelines, enabling real-world implementation.
Cell source
Patient-Derived (CRC Tumor Biopsies, Multi-Center)
Application
Chemotherapy Selection
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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