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INTESTINAL Publication-derived

Intestinal Organ-on-Chip Models

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Source Shin et al. · University of Texas at Austin, USA · 10.1016/j.isci.2019.04.037

Authors: Shin W, Hinojosa CD, Ingber DE, Kim HJ Duration: 14 days Cell source: Primary (Human Intestinal Organoid-Derived Cells)

Abstract

Developed an independent gut-on-a-chip platform using primary human organoid-derived cells with peristalsis-mimicking mechanical strain and continuous flow. The chip supported spontaneous villus-like morphogenesis, differentiation of all four intestinal cell lineages, and formation of a functional MUC2 mucus layer.

Cell source
Primary (Human Intestinal Organoid-Derived Cells)
Application
Intestinal Physiology

No step-by-step SOP yet

OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.

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