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INTESTINAL Publication-derived
Small Intestinal Organoids for Disease Modelling
No SOP yet
Source Senger et al. · Massachusetts General Hospital, Boston, USA · 10.1038/mi.2015.36
Authors: Senger S, Sapone A, Fiorentino MR, Mazzarella G, Larazattera M, Fasano A Duration: 21 days Cell source: Primary (Human Duodenal Biopsies from Celiac and Control Patients)
Abstract
Established duodenal organoids from celiac disease patients that recapitulate gliadin-induced barrier dysfunction through zonulin release and tight junction disassembly. Celiac-derived organoids showed enhanced innate immune responses compared to controls, providing a platform for celiac drug development.
Cell source
Primary (Human Duodenal Biopsies from Celiac and Control Patients)
Application
Celiac Disease Modeling
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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