INTESTINAL Publication-derived

CFTR Organoid Biobank Across 500+ CF Genotypes

Source Amaral et al. · HIT-CF Europe Consortium (Multi-Center)

👤 Amaral MD, Beekman JM, on behalf of the HIT-CF Consortium ⏱ 6720 min 🧫 Primary (Human Rectal Biopsies — 500+ CF Patients, Pan-European Collection)

Abstract

Established the world's largest CF organoid biobank spanning 500+ genotypes across 25+ European centers with standardized forskolin-induced swelling protocols. This infrastructure enables drug access for ultra-rare mutations and supports regulatory biomarker qualification.

Cell source

Primary (Human Rectal Biopsies — 500+ CF Patients, Pan-European Collection)

Application

Pan-European CF Biobank

Full SOP

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Attribution

This SOP was authored by Organthis based on the published method in Amaral et al.. The originating laboratory holds no rights in this SOP and has not endorsed it unless marked Verified.

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