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INTESTINAL Publication-derived

Intestinal Organ-on-Chip Models for Developmental Studies

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Source Nikolaev et al. · EPFL, Lausanne, Switzerland

Authors: Nikolaev M, Mitrofanova O, Broguiere N, Gerber S, Bber D, Kober L, Prados J, Osteil P, Bartber R, Harper JL, Lutolf MP Duration: 21 days Cell source: Primary (Mouse and Human Intestinal Crypts)

Abstract

Created centimeter-scale tubular intestinal organoids with in vivo-like crypt-villus architecture through guided self-organization in microengineered collagen scaffolds with morphogen gradients, achieving months-long stable culture with the most physiological intestinal organoid architecture to date.

Cell source
Primary (Mouse and Human Intestinal Crypts)
Application
Physiological Gut Models

No step-by-step SOP yet

OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.

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