INTESTINAL Publication-derived

Transplantation of Human Intestinal Organoids into Mouse Colon

Source Yui et al. · Tokyo Medical and Dental University, Tokyo, Japan

👤 Yui S, Nakamura T, Sato T, Nemoto Y, Mizutani T, Zheng X, Ichinose S, Nagaishi T, Okamoto R, Tsuchiya K, Clevers H, Watanabe M ⏱ 13440 min 🧫 Primary (Human Colonic Organoids)

Abstract

Achieved the first successful orthotopic transplantation of intestinal organoids into damaged mouse colon, with donor-derived epithelium forming functional self-renewing crypts producing all epithelial lineages, establishing proof-of-principle for organoid-based intestinal regenerative therapy.

Cell source

Primary (Human Colonic Organoids)

Application

Regenerative Medicine

Full SOP

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Attribution

This SOP was authored by Organthis based on the published method in Yui et al.. The originating laboratory holds no rights in this SOP and has not endorsed it unless marked Verified.

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