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SKIN Publication-derived

Skin Spheroids for Regenerative Medicine

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Source Higgins et al. · Durham University / Columbia University, Durham, UK / New York, USA · 10.1073/pnas.1309970110

Authors: Higgins CA, Chen JC, Cerise JE, Jahoda CA, Christiano AM Duration: 14 days Cell source: Primary Human (Dermal Papilla Cells)

Abstract

Demonstrates that 3D spheroid culture restores the hair follicle-inducing capacity of human dermal papilla cells lost in conventional 2D culture. Achieved first human hair follicle neogenesis from cultured cells, driven by Wnt pathway reactivation in 3D conditions.

Cell source
Primary Human (Dermal Papilla Cells)
Application
Hair Follicle Neogenesis

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