SKIN Publication-derived

Derived Spheroids for Hair Follicle Induction

Source Higgins et al. · Durham University / Columbia University, Durham, UK / New York, USA · 10.1073/pnas.1309970110

👤 Higgins CA, Chen JC, Cerise JE, Jahoda CA, Christiano AM ⏱ 6720 min 🧫 Primary Human (Dermal Papilla Cells)

Abstract

Demonstrates that 3D spheroid culture restores the hair follicle-inducing capacity of human dermal papilla cells lost in conventional 2D culture. Achieved first human hair follicle neogenesis from cultured cells, driven by Wnt pathway reactivation in 3D conditions.

Cell source

Primary Human (Dermal Papilla Cells)

Application

Hair Follicle Neogenesis

Full SOP

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Attribution

This SOP was authored by Organthis based on the published method in Higgins et al.. The originating laboratory holds no rights in this SOP and has not endorsed it unless marked Verified.

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