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SKIN Publication-derived
Skin Organoids for Regeneration and Long-Term Culture
No SOP yet
Source Hirsch et al. · Center for Regenerative Medicine, University of Modena and Reggio Emilia, Italy · 10.1038/nature24487
Authors: Hirsch T, Rothoeft T, Teig N, Bauer JW, Pellegrini G, De Rosa L, Scaglione D, Reichelt J, Klausegger A, Kneber R, De Luca M Duration: 120 days Cell source: Patient-Derived (JEB Patient Epidermal Stem Cells)
Abstract
Landmark case report of near-total body surface regeneration from gene-corrected epidermal stem cells in a child with junctional EB. Demonstrated that the human epidermis is sustained by holoclone stem cells and established the feasibility of whole-body skin replacement with gene-corrected grafts.
Cell source
Patient-Derived (JEB Patient Epidermal Stem Cells)
Application
Life-Saving Gene Therapy for JEB
No step-by-step SOP yet
OrganMatch™ lists this published method, but there is no step-by-step SOP for it yet.
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