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934 protocols found

RETINA

Publication-derived

Retinal Embryo Models for Disease Modelling (RT-DS-19)

Source Mellough et al., 2019 · Institute of Genetic Medicine, Newcastle University, Newcastle, United Kingdom · DOI

150 days Human ESC (H9, WiCell); Human iPSC (Neo1 neonatal, AD3 adult) Full SOP · 7 phases · QC included

Disease modelling

RT-DS-19 Full SOP with Academic or a plan

LIVER

Publication-derived

Liver Organ-on-Chip Models for Drug Screening (LV-DS-18)

Source Wang et al., 2018 · Dalian Institute of Chemical Physics, Chinese Academy of Sciences · DOI

48 days Human iPSC Full SOP · 14 phases · QC included

Drug screening

LV-DS-18 Full SOP with Academic or a plan

LIVER

Publication-derived

Steatohepatitis Liver Organoids (2025) (LV-FI-25)

Source Liu et al., 2025 · University of Pennsylvania, Perelman School of Medicine · DOI

30 days Patient-Derived Organoids (MASH), Primary Human Hepatic Stellate Cells, Human Peripheral Blood Monocytes Full SOP · 10 phases · QC included

Disease modelling

LV-FI-25 Full SOP with Academic or a plan

LIVER

Publication-derived

Liver Organoids for Drug Screening and Disease Modelling (2024) (LV-DS-24)

Source Maepa et al., 2024 · University of Cape Town · DOI

30 days Human iPSC Full SOP · 13 phases · QC included

Drug screening

LV-DS-24 Full SOP with Academic or a plan

LUNG

Publication-derived

Lung Cancer Tumouroids for Drug Screening (AW-DS-19)

Source Kim et al., 2019 · Asan Institute for Life Sciences, Seoul, South Korea · DOI

21 days Patient-Derived Lung Cancer Tissues (Multiple Histological Subtypes) Full SOP · 7 phases · QC included

Drug screening

AW-DS-19 Full SOP with Academic or a plan

BRAIN

Publication-derived

Brain Organoids for Infection and Development (BN-DS-17)

Source Li et al., 2017 · The Whitehead Institute for Biomedical Research · DOI

84 days Human ESC (WIBR1, WIBR2, WIBR3 lines) Full SOP · 7 phases · QC included

Disease modelling

BN-DS-17 Full SOP with Academic or a plan

PANCREAS

Publication-derived

Pancreatic Ductal Adenocarcinoma Organoids for Drug Screening (PN-DS-18)

Source Seino et al., 2018 · Keio University School of Medicine, Department of Gastroenterology, Tokyo · DOI

24 days Patient-Derived PDAC Full SOP · 8 phases · QC included

Drug screening

PN-DS-18 Full SOP with Academic or a plan

INTESTINAL

Publication-derived

Colorectal Cancer Colonic Tumouroids for Regenerative Medicine (IN-CA-17)

Source Fumagalli et al., 2017 · Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center (UMC) Utrecht · DOI

112 days Human intestinal stem cells, normal donor and patient-derived colon tissue Full SOP · 12 phases · QC included

Disease modelling

IN-CA-17 Full SOP with Academic or a plan

RETINA

Publication-derived

Inherited Retinal Disease Organoids (RT-DS-25)

Source Lee et al., 2025 · Seoul National University College of Medicine · DOI

30 days Patient-Derived iPSC (Inherited Retinal Diseases) Full SOP · 6 phases · QC included

Drug screening

RT-DS-25 Full SOP with Academic or a plan

BRAIN

Publication-derived

Multiple Sclerosis Brain Organoids (BN-IF-24)

Source Fagiani et al., 2024 · IRCCS San Raffaele Scientific Institute, Milan, Italy · DOI

56 days Human iPSC-derived Neural Precursor Cells (NPCs) and iPSC-derived Microglia Full SOP · 5 phases · QC included

Disease modelling

BN-IF-24 Full SOP with Academic or a plan

BRAIN

Publication-derived

Autism Spectrum Disorder Cortical Organoids with Single-Cell Profiling (BN-DS-23)

Source Jang et al., 2023 · DGIST (Daegu Gyeongbuk Institute of Science and Technology) · DOI

75 days Patient-Derived iPSC (CNTNAP2-associated ASD); Mouse Neural Tissue (Cntnap2 KO) Full SOP · 5 phases · QC included

Disease modelling

BN-DS-23 Full SOP with Academic or a plan

BRAIN

Publication-derived

Cerebral Amyloid Angiopathy Brain Models (BN-DS-20)

Source Blanchard et al., 2020 · Picower Institute for Learning and Memory, Massachusetts Institute of Technology · DOI

30 days Human iPSC Full SOP · 12 phases · QC included

Disease modelling

BN-DS-20 Full SOP with Academic or a plan

BRAIN

Publication-derived

Brain Organoids for Regenerative Medicine with Vasculature (BN-TX-18)

Source Daviaud et al., 2018 · Fishberg Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai · DOI

60 days Human ESC (H9 hES cells) Full SOP · 7 phases · QC included

Regenerative medicine

BN-TX-18 Full SOP with Academic or a plan

INTESTINAL

Publication-derived

Metastatic Colorectal Cancer Colonic Tumouroids for Drug Screening (IN-DS-15)

Source Weeber et al., 2015 · The Netherlands Cancer Institute, Amsterdam · DOI

90 days Patient-Derived Tumor Biopsy (Metastatic Colorectal Cancer) Full SOP · 5 phases · QC included

Drug screening

IN-DS-15 Full SOP with Academic or a plan

RETINA

Publication-derived

Retinal Organoids for Drug Screening and Development (RT-DS-20)

Source Fligor et al., 2020 · Indiana University–Purdue University Indianapolis / Indiana University School of Medicine · DOI

200 days Human hPSC (hESC and hiPSC) Full SOP · 3 phases · QC included

Drug screening

RT-DS-20 Full SOP with Academic or a plan

LIVER

Publication-derived

Fatty Liver Disease Organoids with Gene Editing (LV-DS-23)

Source Hendriks et al., 2023 · Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands · DOI

30 days Human fetal hepatocyte organoids Full SOP · 9 phases · QC included

Drug screening

LV-DS-23 Full SOP with Academic or a plan

RETINA

Publication-derived

Retinal Organoids for Disease and Development (2021) (RT-DS-21)

Source Afanasyeva et al., 2021 · Radboud University Medical Center · DOI

180 days Human iPSC Full SOP · 4 phases · QC included

Disease modelling

RT-DS-21 Full SOP with Academic or a plan

LIVER

Publication-derived

Antiretroviral Therapy-Induced Liver Injury Organoids (LV-DS-25)

Source Maepa et al., 2025 · University of Cape Town · DOI

30 days Human iPSC Full SOP · 10 phases · QC included

Drug screening

LV-DS-25 Full SOP with Academic or a plan

BRAIN

Publication-derived

Schizophrenia Brain Organoids with Single-Cell Profiling (BN-DS-24)

Source Sawada et al., 2024 · Lieber Institute for Brain Development · DOI

241 days Patient-Derived iPSC (Schizophrenia) and Control iPSC Full SOP · 8 phases · QC included

Disease modelling

BN-DS-24 Full SOP with Academic or a plan

BRAIN

Publication-derived

Multiple Sclerosis Brain Organoids with Microglia (BN-DS-25)

Source Fagiani et al., 2025 · IRCCS San Raffaele Scientific Institute, Milan, Italy · DOI

56 days Patient-Derived iPSC (Relapsing-Remitting Multiple Sclerosis) Full SOP · 9 phases · QC included

Disease modelling

BN-DS-25 Full SOP with Academic or a plan

LIVER

Publication-derived

Biliary Atresia Models (LV-DS-24)

Source Xiao et al., 2024 · Department of Pediatric Surgery and Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China · DOI

60 days Primary human hepatic mononuclear cells (LMNC) and peripheral blood mononuclear cells (PBMC) from biliary atresia patients; human biliary organoids from hepatoblastoma patients; human cholangiocyte H69 cell line Full SOP · 13 phases · QC included

Disease modelling

LV-DS-24 Full SOP with Academic or a plan

INTESTINAL

Publication-derived

Colonic Organoids for Developmental Studies (2013) (IN-SC-13)

Source Wang et al., 2013 · Stowers Institute for Medical Research · DOI

100 days Mouse Lgr5-GFP ISCs; Human small intestinal crypts and isolated IECs Full SOP · 8 phases · QC included

Developmental biology

IN-SC-13 Full SOP with Academic or a plan

BRAIN

Publication-derived

Medulloblastoma Hindbrain Organoids with Gene Editing (BN-DS-24)

Source van Essen et al., 2024 · Nuffield Department of Clinical Neurosciences, University of Oxford · DOI

90 days Human iPSC Full SOP · 11 phases · QC included

Disease modelling

BN-DS-24 Full SOP with Academic or a plan

LIVER

Publication-derived

Liver 2D Cell Cultures for Drug Screening (LV-DS-15)

Source Ng et al., 2015 · Massachusetts Institute of Technology · DOI

28 days Human iPSC Full SOP · 7 phases · QC included

Drug screening

LV-DS-15 Full SOP with Academic or a plan