Skip to content

Browse Protocols

Wrote one of these methods? Find yours by DOI and review the entry.

Find your method
934 protocols found
934 protocols found
KIDNEY
Publication-derived

Polycystic Kidney Disease Organoids (KD-DS-17)

Source Cruz et al., 2017 · University of Washington School of Medicine, Division of Nephrology · DOI

Duration: 87 days Cell source: Human ESC (WA09/H9); Human iPSC (WTC11); CRISPR-targeted PKD1[-/-] or PKD2[-/-] hPSC mutants Full SOP · 11 phases · QC included
Disease modelling
KD-DS-17 Full SOP with Academic or a plan
BRAIN
Publication-derived

Young-Onset Parkinson's Disease Midbrain Organoids (BN-DS-22)

Source Zhu et al., 2022 · Nanjing Medical University

Duration: 56 days Cell source: Patient-Derived iPSC (Young-Onset Parkinson's Disease - PINK1 mutation) Full SOP · 13 phases · QC included
Disease modelling
BN-DS-22 Full SOP with Academic or a plan
INTESTINAL
Publication-derived

Colorectal Cancer Colonic Tumouroids (2020) (IN-DS-20)

Source Engel et al., 2020 · Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia · DOI

Duration: 15 days Cell source: Patient-Derived Tumor Tissue (Colorectal Cancer) Full SOP · 7 phases · QC included
Drug screening
IN-DS-20 Full SOP with Academic or a plan
INTESTINAL
Publication-derived

Crohn's Disease Small Intestinal Organoids (IN-DS-18)

Source Suzuki et al., 2018 · Tokyo Medical and Dental University · DOI

Duration: 23 days Cell source: Patient-Derived iPSC (Crohn's Disease) Full SOP · 7 phases · QC included
Disease modelling
IN-DS-18 Full SOP with Academic or a plan
BRAIN
Publication-derived

Down Syndrome and Alzheimer's Disease Cerebral Organoids (BN-DS-22)

Source Jin et al., 2022 · Rutgers University · DOI

Duration: 56 days Cell source: Human iPSC-derived primitive macrophage progenitors (PMPs) from Down syndrome patients and controls Full SOP · 17 phases · QC included
Disease modelling
BN-DS-22 Full SOP with Academic or a plan
LIVER
Publication-derived

Acute Liver Failure Organoids (LV-DS-25)

Source Raggi et al., 2025 · CHU Sainte-Justine Research Center, Montreal, Canada · DOI

Duration: 90 days Cell source: Human iPSC Full SOP · 8 phases · QC included
Disease modelling
LV-DS-25 Full SOP with Academic or a plan
SKIN
Publication-derived

Skin Organoids for Disease and Development (SK-DS-22)

Source Ramovs et al., 2022 · Leiden University Medical Center, Department of Anatomy and Embryology · DOI

Duration: 130 days Cell source: Human iPSC (hiPSC lines LUMCi045-A1, LUMCi046-A1, WT2) Full SOP · 9 phases · QC included
Disease modelling
SK-DS-22 Full SOP with Academic or a plan
SKIN
Publication-derived

COVID-19 Skin Organoids (SK-DS-22)

Source Ma et al., 2022 · Peking Union Medical College Hospital, Chinese Academy of Medical Sciences · DOI

Duration: 144 days Cell source: Human iPSC Full SOP · 9 phases · QC included
Disease modelling
SK-DS-22 Full SOP with Academic or a plan
BRAIN
Publication-derived

Hindbrain Organoids for Disease and Development (BN-DS-15)

Source Muguruma et al., 2015 · RIKEN Center for Developmental Biology · DOI

Duration: 148 days Cell source: Human ESC Full SOP · 4 phases · QC included
Disease modelling
BN-DS-15 Full SOP with Academic or a plan
SKIN
Publication-derived

Skin Organoids for Disease Modelling (2024) (SK-DS-24)

Source Kim et al., 2024 · Adult Stem Cell Research Center and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University · DOI

Duration: 130 days Cell source: Human iPSC (line CMC003) Full SOP · 18 phases · QC included
Disease modelling
SK-DS-24 Full SOP with Academic or a plan
LIVER
Publication-derived

Biliary Organoids for Disease Modelling with Fluorescent Reporters (LV-DS-19)

Source Koike et al., 2019 · Cincinnati Children's Hospital Medical Center · DOI

Duration: 90 days Cell source: Human iPSC, Human ESC Full SOP · 7 phases · QC included
Disease modelling
LV-DS-19 Full SOP with Academic or a plan
BRAIN
Publication-derived

Glioblastoma Brain Organoids (2024) (BN-CA-24)

Source Watanabe et al., 2024 · UConn Health Brain and Spine Institute · DOI

Duration: 40 days Cell source: Patient-Derived GSC (Glioblastoma Stem Cells) Full SOP · 7 phases · QC included
Disease modelling
BN-CA-24 Full SOP with Academic or a plan
OTHER
Publication-derived

Mitochondrial Encephalomyopathy Organoids

Source Winanto et al., 2020 · Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore · DOI

Duration: 42 days Cell source: Patient-Derived iPSC (MELAS with A3243G mtDNA mutation) Full SOP · 10 phases · QC included
Disease modelling
Full SOP with Academic or a plan
BRAIN
Publication-derived

Fungal Meningitis/Cryptococcal Infection Brain Organ-on-Chip Models (BN-DS-21)

Source DOI

Duration: 7 days Cell source: Human fetal NSC (13 weeks gestation), human cerebral microvascular endothelial cells (hCMEC/D3), human brain microvascular pericytes (HBVP) Full SOP · 17 phases · QC included
Disease modelling
BN-DS-21 Full SOP with Academic or a plan
INTESTINAL
Publication-derived

Colorectal Cancer Colonic Tumouroids for Disease Modelling (2016) (IN-DS-16)

Source Fessler et al., 2016 · Laboratory for Experimental Oncology and Radiobiology (LEXOR), Center for Experimental Molecular Medicine (CEMM), Academic Medical Center (AMC), University of Amsterdam · DOI

Duration: 14 days Cell source: Human iPSC (genetically engineered BRAF[V600E]); Patient-derived tubuler adenoma and normal colon organoids Full SOP · 10 phases · QC included
Disease modelling
IN-DS-16 Full SOP with Academic or a plan
LIVER
Publication-derived

Drug-Induced Liver Injury Organ-on-Chip Models in High-Throughput Format (LV-DI-23)

Source Zhang et al., 2023 · University of Michigan · DOI

Duration: 14 days Cell source: Human iPSC (fibroblast-derived) Full SOP · 10 phases · QC included
Drug screening
LV-DI-23 Full SOP with Academic or a plan
BRAIN
Publication-derived

Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Brain Organoids (2021) (BN-DS-21)

Source Szebényi et al., 2021 · John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge · DOI

Duration: 240 days Cell source: Human iPSC Full SOP · 10 phases · QC included
Disease modelling
BN-DS-21 Full SOP with Academic or a plan
BRAIN
Publication-derived

Young-Onset Parkinson's Disease Midbrain Organoids with Single-Cell Profiling (BN-DS-22)

Source Zhu et al., 2022 · School of Pharmacy, Nanjing Medical University, China · DOI

Duration: 50 days Cell source: Patient-Derived iPSC (Young-onset Parkinson's disease, PINK1 mutation) Full SOP · 7 phases · QC included
Drug screening
BN-DS-22 Full SOP with Academic or a plan
BRAIN
Publication-derived

Cortical 2D Cell Cultures for Disease Modelling with Enhanced Maturation (BN-DS-19)

Source Miguel et al., 2019 · Normandie Univ, UNIROUEN, Inserm U1245 and Rouen University Hospital · DOI

Duration: 25 days Cell source: Human iPSC Full SOP · 8 phases · QC included
Disease modelling
BN-DS-19 Full SOP with Academic or a plan
GASTRIC
Publication-derived

Gastric Cancer Tumouroids for Developmental Studies (GS-DS-18)

Source Yan et al., 2018 · Department of Pathology, The University of Hong Kong, Queen Mary Hospital · DOI

Duration: 90 days Cell source: Patient-Derived Primary Gastric Cancer and Normal Gastric Epithelial Tissue Full SOP · 11 phases · QC included
Drug screening
GS-DS-18 Full SOP with Academic or a plan
LIVER
Publication-derived

Hepatocellular Carcinoma Liver Organoids for Biobanking (LV-CA-18)

Source Nuciforo et al., 2018 · University Hospital Basel, University of Basel · DOI

Duration: 28 days Cell source: Patient-Derived Hepatocellular Carcinoma (HCC) and Intrahepatic Cholangiocarcinoma (CCC) cells from needle biopsies Full SOP · 8 phases · QC included
Drug screening
LV-CA-18 Full SOP with Academic or a plan
CARDIAC
Publication-derived

Cardiac Organoids for Toxicity Testing with Vasculature (CD-DS-24)

Source Yang et al., 2024 · Department of Cardiovascular Surgery of the First Affiliated Hospital & Institute for Cardiovascular Science, Soochow University, Suzhou, China · DOI

Duration: 72 days Cell source: Human iPSC Full SOP · 17 phases · QC included
Safety & toxicology
CD-DS-24 Full SOP with Academic or a plan
PANCREAS
Publication-derived

Pancreatic Ductal Adenocarcinoma Organoids for Disease Modelling (PN-DS-18)

Source Tiriac et al., 2018 · Cold Spring Harbor Laboratory · DOI

Duration: 90 days Cell source: Patient-Derived iPSC (Pancreatic Cancer) Full SOP · 10 phases · QC included
Drug screening
PN-DS-18 Full SOP with Academic or a plan
VASCULAR
Publication-derived

Vascular Organoids for Disease Modelling with Gene Editing (VS-DS-24)

Source Ahn et al., 2024 · Korea Research Institute of Bioscience and Biotechnology (KRIBB) · DOI

Duration: 18 days Cell source: Patient-Derived iPSC (CADASIL) Full SOP · 15 phases · QC included
Disease modelling
VS-DS-24 Full SOP with Academic or a plan