Browse Protocols

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934 protocols found

BRAIN

Publication-derived

Herpes Simplex Encephalitis Cerebral Organoids (BN-DS-23)

Source Rybak-Wolf et al., 2023 · Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine in the Helmholtz Association · DOI

60 days Human iPSC Full SOP · 5 phases · QC included

Disease modelling

BN-DS-23 Full SOP with Academic or a plan

BRAIN

Publication-derived

Cerebral Organoids for Disease and Development (2024) (BN-DS-24)

Source van der Geest et al., 2024 · University Medical Center Utrecht · DOI

90 days Patient-Derived iPSC (C9ORF72-ALS/FTD), Presymptomatic C9-HRE Carriers, Healthy Control iPSC Full SOP · 13 phases · QC included

Disease modelling

BN-DS-24 Full SOP with Academic or a plan

BRAIN

Publication-derived

Miller-Dieker Syndrome Brain Organoids (BN-DS-17)

Source Bershteyn et al., 2017 · Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco · DOI

70 days Patient-Derived iPSC (Miller-Dieker Syndrome) Full SOP · 9 phases · QC included

Disease modelling

BN-DS-17 Full SOP with Academic or a plan

BRAIN

Publication-derived

Alzheimer's Disease Cerebral Organoids with Astrocytes (BN-DS-22)

Source Huang et al., 2022 · State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences · DOI

60 days Human iPSC Full SOP · 5 phases · QC included

Disease modelling

BN-DS-22 Full SOP with Academic or a plan

BRAIN

Publication-derived

Brain Organoids for Infection and Neuroinflammation (BN-DS-24)

Source Capendale et al., 2024 · Amsterdam UMC, Academic Medical Center, Amsterdam Institute for Infection and Immunity · DOI

77 days Human iPSC Full SOP · 11 phases · QC included

Disease modelling

BN-DS-24 Full SOP with Academic or a plan

SKIN

Publication-derived

Epidermolysis Bullosa Skin Organoids (SK-DS-22)

Source Ramovs et al., 2022 · Leiden University Medical Center, Department of Anatomy and Embryology · DOI

130 days Human iPSC (LUMCi045-A1, LUMCi046-A1, WT2) Full SOP · 12 phases · QC included

Disease modelling

SK-DS-22 Full SOP with Academic or a plan

RETINA

Publication-derived

Glaucoma and Ocular Neuropathies Retinal Organoids (RT-DS-21)

Source Wagstaff et al., 2021 · Department of Clinical Genetics, Amsterdam UMC, University of Amsterdam · DOI

160 days Human ESC (H1, WiCell) Full SOP · 5 phases · QC included

Disease modelling

RT-DS-21 Full SOP with Academic or a plan

BRAIN

Publication-derived

Bacterial Meningitis Choroid Plexus Organoids (BN-DS-25)

Source Zhao et al., 2025 · Host-Microbe Interactomics, Department Animal Science, Wageningen University & Research · DOI

40 days Human iPSC (EDi002-A line) Full SOP · 10 phases · QC included

Disease modelling

BN-DS-25 Full SOP with Academic or a plan

LIVER

Publication-derived

Liver Organoids for Drug Screening in High-Throughput Format

Source Shrestha et al. · University of North Texas, Department of Biomedical Engineering · DOI

33 days Human iPSC Full SOP · 5 phases · QC included

Drug screening

Full SOP with Academic or a plan

BRAIN

Publication-derived

Familial Parkinson's Disease Midbrain Organoids (BN-DS-23)

Source Becerra-Calixto et al., 2023 · Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, McGovern Medical School, University of Texas Health Science Center at Houston · DOI

180 days Patient-Derived iPSC (Familial Parkinson's Disease with SNCA triplication) Full SOP · 7 phases · QC included

Disease modelling

BN-DS-23 Full SOP with Academic or a plan

BRAIN

Publication-derived

HIV-Associated Neurocognitive Disorder Cerebral Organoids (BN-DS-24)

Source Boreland et al., 2024 · Rutgers Robert Wood Johnson Medical School, Child Health Institute of New Jersey · DOI

144 days Human iPSC Full SOP · 11 phases · QC included

Disease modelling

BN-DS-24 Full SOP with Academic or a plan

SKIN

Publication-derived

Skin Organoids for Drug Screening with Immune Cells (SK-DS-25)

Source Mostina et al., 2025 · The University of Queensland, Brisbane, QLD, Australia · DOI

115 days Human iPSC Full SOP · 5 phases · QC included

Drug screening

SK-DS-25 Full SOP with Academic or a plan

LIVER

Publication-derived

Liver Bioprinted and Engineered Tissues for Disease Modelling (LV-DS-18)

Source Ng et al., 2018 · King's College London, Centre for Stem Cells and Regenerative Medicine & Institute for Liver Studies · DOI

14 days Human iPSC-derived hepatic progenitors Full SOP · 3 phases · QC included

Disease modelling

LV-DS-18 Full SOP with Academic or a plan

LIVER

Publication-derived

Alcohol-Related Liver Disease Organoids (LV-DS-20)

Source Angireddy et al., 2020 · University of Pennsylvania, School of Veterinary Medicine, Department of Biomedical Sciences · DOI

21 days Human HepaRG hepatocyte cell line (derived from hepatic tumors but differentiated to functional hepatocytes) Full SOP · 9 phases · QC included

Safety & toxicology

LV-DS-20 Full SOP with Academic or a plan

RETINA

Publication-derived

Retinal Organoids for Disease Modelling (No. 2)

Source Children's Hospital Los Angeles (CHLA)

42 days Human ESC (WA09) and Human iPSC Full SOP · 9 phases · QC included

Disease modelling

Full SOP with Academic or a plan

BRAIN

Publication-derived

Brain Ribosomopathy Cerebral Organoids (BN-DS-24)

Source Zhang et al., 2024 · University of Southern California · DOI

15 days Human iPSC Full SOP · 16 phases · QC included

Drug screening

BN-DS-24 Full SOP with Academic or a plan

BRAIN

Publication-derived

Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Brain Models (BN-DS-22)

Source Meijboom et al., 2022 · University of Massachusetts Medical School and University of Miami Miller School of Medicine · DOI

60 days Patient-Derived iPSC, Primary cortical neurons from C9ORF72 transgenic mice Full SOP · 5 phases · QC included

Disease modelling

BN-DS-22 Full SOP with Academic or a plan

BRAIN

Publication-derived

Cortical 2D Cell Cultures for Disease Modelling (BN-TX-12)

Source Mariani et al., 2012 · Yale University School of Medicine · DOI

70 days Human iPSC Full SOP · 4 phases · QC included

Developmental biology

BN-TX-12 Full SOP with Academic or a plan

LUNG

Publication-derived

Lung Organoids for Infection Studies with Immune Cells (AW-DS-24)

Source Catarino, 2024 · Center for Biomedical Research of Aragón, University of Zaragoza

24 days Human lung tissue (adult tissue from tumour resection surgeries); Human iPSC-derived or PBMC-derived macrophages and NK cells Full SOP · 8 phases · QC included

Disease modelling

AW-DS-24 Full SOP with Academic or a plan

BRAIN

Publication-derived

Ischaemic Stroke Cerebral Organoids (BN-DS-23)

Source Cao et al., 2023 · Department of Pharmacology, School of Pharmacy, Nanjing Medical University · DOI

180 days Human iPSC (IMR-90-4), Human ESC (H9), Human iPSC (H9-CAG-ChR2-EYFP) Full SOP · 9 phases · QC included

Disease modelling

BN-DS-23 Full SOP with Academic or a plan

GASTRIC

Publication-derived

Gastric Cancer Tumouroids for Disease Modelling (GS-CA-19)

Source Seidlitz et al., 2019 · Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden · DOI

72 days Human gastric cancer and normal gastric tissue from surgical resection specimens Full SOP · 9 phases · QC included

Drug screening

GS-CA-19 Full SOP with Academic or a plan

BRAIN

Publication-derived

Medulloblastoma Brain Models (BN-DS-23)

Source Contenti et al., 2023 · Université Côte d'Azur, INSERM U1065, C3M, Nice, France · DOI

92 days Human iPSC (cerebellar organoids); Human medulloblastoma cell lines (HDMB-03, D-458) Full SOP · 11 phases · QC included

Drug screening

BN-DS-23 Full SOP with Academic or a plan

BRAIN

Publication-derived

Cortical Organoids for Disease Modelling (2008) (BN-DS-08)

Source Eiraku et al., 2008 · RIKEN Center for Developmental Biology, Kobe, Japan · DOI

46 days Mouse ESC (EB5), Human ESC Full SOP · 7 phases · QC included

Disease modelling

BN-DS-08 Full SOP with Academic or a plan

BRAIN

Publication-derived

Brain Organoids for Infection Studies (2019) (BN-DS-19)

Source Xu et al., 2019 · State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences · DOI

72 days Human ESC (H9), Patient-Derived hNPC (line 15167) Full SOP · 13 phases · QC included

Disease modelling

BN-DS-19 Full SOP with Academic or a plan