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934 protocols found
934 protocols found
LIVER
Publication-derived

Liver Organoids for Drug Screening in Suspension (LV-DS-23)

Source Harrison et al., 2023 · University of Oslo, Institute of Basic Medical Sciences, Hybrid Technology Hub-Centre of Excellence · DOI

Duration: 20 days Cell source: Human PSC (H1 ESC, 207 ESC, AG27 iPSC) Full SOP · 6 phases · QC included
Drug screening
LV-DS-23 Full SOP with Academic or a plan
INTESTINAL
Publication-derived

Clostridium Difficile Infection Intestinal Organoids (IN-DS-15)

Source Engevik et al., 2015 · University of Cincinnati College of Medicine · DOI

Duration: 7 days Cell source: Human intestinal organoids (HIOs) derived from human pluripotent stem cells (hPSC) Full SOP · 9 phases · QC included
Disease modelling
IN-DS-15 Full SOP with Academic or a plan
INTESTINAL
Publication-derived

Intestinal Organoids for Disease Modelling (2014) (IN-DS-14)

Source Bigorgne et al., 2014 · INSERM U768, Hôpital Necker Enfants-Malades, Paris, France · DOI

Duration: 20 days Cell source: Human Patient-Derived iPSC (Multiple Intestinal Atresia with Combined Immunodeficiency) Full SOP · 8 phases · QC included
Disease modelling
IN-DS-14 Full SOP with Academic or a plan
RETINA
Publication-derived

Retinal Organoids for Disease Modelling (2018) (RT-DS-18)

Source DiStefano et al., 2018 · National Eye Institute (NEI), National Institutes of Health · DOI

Duration: 32 days Cell source: Mouse ESC (Nrl-GFP) Full SOP · 5 phases · QC included
Disease modelling
RT-DS-18 Full SOP with Academic or a plan
LIVER
Publication-derived

Hepatoblastoma Liver Organoids for Disease Modelling (LV-CA-22)

Source Yang et al., 2022 · State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai · DOI

Duration: 120 days Cell source: Human fetal hepatoblasts (8-12 weeks post-coitum) Full SOP · 9 phases · QC included
Disease modelling
LV-CA-22 Full SOP with Academic or a plan
LUNG
Publication-derived

Airway Organoids for Toxicity Testing (AW-DS-18)

Source Hui et al., 2018 · Li Ka Shing Faculty of Medicine, The University of Hong Kong · DOI

Duration: 72 days Cell source: Human lung stem cells derived from non-tumour lung tissue Full SOP · 10 phases · QC included
Safety & toxicology
AW-DS-18 Full SOP with Academic or a plan
BRAIN
Publication-derived

Bacterial Meningitis Choroid Plexus Organoids for Infection Studies (BN-DS-25)

Source Zhao et al., 2025 · Wageningen University & Research · DOI

Duration: 40 days Cell source: Human iPSC Full SOP · 13 phases · QC included
Disease modelling
BN-DS-25 Full SOP with Academic or a plan
BRAIN
Publication-derived

Cerebral Organoids for Disease Modelling and Neuroinflammation (BN-IF-23)

Source Hong et al., 2023 · Western University of Health Sciences, College of Veterinary Medicine, Pomona, CA · DOI

Duration: 90 days Cell source: Patient-Derived iPSC (ALS-PDC); Human iPSC (healthy control) Full SOP · 9 phases · QC included
Disease modelling
BN-IF-23 Full SOP with Academic or a plan
BRAIN
Publication-derived

Cerebral Palsy with Intellectual Disability Brain Organoids (BN-DS-24)

Source Sun et al., 2024 · Guangzhou Women and Children's Medical Center, Guangzhou Medical University · DOI

Duration: 66 days Cell source: Human ESC Full SOP · 4 phases · QC included
Disease modelling
BN-DS-24 Full SOP with Academic or a plan
LIVER
Publication-derived

Hepatitis B Liver Organoids for Disease Modelling (LV-DS-18)

Source Nie et al., 2018 · Department of Regenerative Medicine, Yokohama City University Graduate School of Medicine · DOI

Duration: 42 days Cell source: Human iPSC Full SOP · 10 phases · QC included
Disease modelling
LV-DS-18 Full SOP with Academic or a plan
BRAIN
Publication-derived

Down Syndrome Brain Organoids with Interneurons (BN-DS-19)

Source Xu et al., 2019 · Rutgers University · DOI

Duration: 180 days Cell source: Patient-Derived iPSC (Down syndrome) Full SOP · 7 phases · QC included
Disease modelling
BN-DS-19 Full SOP with Academic or a plan
LIVER
Publication-derived

Liver Organoids for Drug Screening (2024) (LV-DI-24)

Source Romaldini et al., 2024 · Istituto Italiano di Tecnologia (IIT), Genoa, Italy · DOI

Duration: 29 days Cell source: Human iPSC-derived hepatocytes (upcyte UHHs), human primary endothelial cells (upcyte LSECs), human bone marrow-derived mesenchymal stromal cells (hbmMSCs) Full SOP · 5 phases · QC included
Drug screening
LV-DI-24 Full SOP with Academic or a plan
GASTRIC
Publication-derived

Gastric Organoids for Disease and Development (GS-DS-15)

Source Huch et al., 2015 · Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge · DOI

Duration: 34 days Cell source: Human ESC, Human iPSC, Adult Stem Cell Full SOP · 7 phases · QC included
Disease modelling
GS-DS-15 Full SOP with Academic or a plan
BRAIN
Publication-derived

Down Syndrome Cerebral Organoids with Gene Editing (BN-DS-21)

Source Tang et al., 2021 · Department of Stem Cell and Neural Regeneration, State Key Laboratory of Reproductive Medicine, Nanjing Medical University · DOI

Duration: 70 days Cell source: Patient-Derived iPSC (Down syndrome trisomy 21) Full SOP · 11 phases · QC included
Disease modelling
BN-DS-21 Full SOP with Academic or a plan
REPRODUCTIVE
Publication-derived

Ovarian Cancer Reproductive Tumouroids (RP-DS-19)

Source Kopper et al., 2019 · Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and UMC Utrecht · DOI

Duration: 14 days Cell source: Patient-Derived Tumor (Ovarian Cancer) Full SOP · 4 phases · QC included
Drug screening
RP-DS-19 Full SOP with Academic or a plan
SKIN
Publication-derived

Skin Organoids for Regeneration and Disease Modelling (SK-DS-24)

Source Shafiee et al., 2024 · University of Queensland, Herston Biofabrication Institute · DOI

Duration: 125 days Cell source: Human iPSC (skin fibroblast-derived and placental CD34+-derived) Full SOP · 8 phases · QC included
Disease modelling
SK-DS-24 Full SOP with Academic or a plan
BRAIN
Publication-derived

Angelman Syndrome Cerebral Organoids (BN-DS-20)

Source Sen et al., 2020 · Department of Chemical and Biomolecular Engineering, North Carolina State University · DOI

Duration: 17 days Cell source: Human ESC (H9, H1), Human iPSC, Patient-Derived iPSC (Angelman syndrome) Full SOP · 5 phases · QC included
Drug screening
BN-DS-20 Full SOP with Academic or a plan
BRAIN
Publication-derived

Cerebral Organoids for Disease Modelling with Vasculature (2024) (BN-DS-24)

Source Lau et al., 2024 · University of Toronto, Department of Molecular Genetics · DOI

Duration: 12 days Cell source: Human hESC (H9) Full SOP · 10 phases · QC included
Disease modelling
BN-DS-24 Full SOP with Academic or a plan
BRAIN
Publication-derived

Bipolar Disorder Midbrain Organoids

Source Meyer et al. · Department of Genetics, Blavatnik Institute, Harvard Medical School; Wyss Institute for Biologically Inspired Engineering, Harvard University; BD2: Breakthrough Discoveries for thriving with Bipolar Disorder · DOI

Duration: 56 days Cell source: Patient-Derived iPSC (Bipolar Disorder); Healthy Control iPSC Full SOP · 9 phases · QC included
Drug screening
Full SOP with Academic or a plan
RETINA
Publication-derived

Retinal Organoids for Disease Modelling (2015) (RT-DS-15)

Source Kuwahara et al., 2015 · RIKEN Center for Developmental Biology, Kobe, Japan · DOI

Duration: 150 days Cell source: Human ESC (hESC; KhES-1 line; Venus-knock-in reporter lines Rx::Venus, Rx::AcGFP, Crx::Venus) Full SOP · 7 phases · QC included
Disease modelling
RT-DS-15 Full SOP with Academic or a plan
BRAIN
Publication-derived

Huntington's Disease Striatal Organoids (BN-DS-22)

Source Liu et al., 2022 · Nanjing Medical University · DOI

Duration: 60 days Cell source: Human iPSC (Patient-Derived iPSC (Huntington's disease with 75 CAG repeats); Control iPSC H9 and IMR90-4) Full SOP · 8 phases · QC included
Disease modelling
BN-DS-22 Full SOP with Academic or a plan
RETINA
Publication-derived

Retinal Organoids for Disease and Development (2020) (RT-DS-20)

Source Regent et al., 2020 · Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD

Duration: 200 days Cell source: Human iPSC, Human ESC Full SOP · 4 phases · QC included
Disease modelling
RT-DS-20 Full SOP with Academic or a plan
INTESTINAL
Publication-derived

Intestinal Organoids for Infection and Regeneration (IN-DS-14)

Source Nigro et al., 2014 · Institut Pasteur, Paris · DOI

Duration: 72 days Cell source: Mouse Lgr5+ intestinal stem cells Full SOP · 10 phases · QC included
Disease modelling
IN-DS-14 Full SOP with Academic or a plan
GASTRIC
Publication-derived

Gastric Organoids for Developmental Studies (2019) (GS-TX-19)

Full SOP · 7 phases · QC included
Developmental biology
GS-TX-19 Full SOP with Academic or a plan