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934 protocols found
934 protocols found
BRAIN
Publication-derived

Cerebral Organoids for Disease and Development

Source Zhu et al. · Rutgers University, New Brunswick, NJ, USA · DOI

Duration: 60 days Cell source: Human iPSC / Human ESC
Developmental biology
No SOP yet
BRAIN
Publication-derived

Brain Organoids for Drug Screening with Astrocytes

Source Madhavan et al. · Case Western Reserve University, Cleveland, OH, USA · DOI

Duration: 150 days Cell source: Human iPSC
Drug screening
No SOP yet
BRAIN
Publication-derived

Brain Models for Disease Modelling (2013)

Source Miller et al. · Salk Institute for Biological Studies, La Jolla, CA, USA · DOI

Duration: 90 days Cell source: Patient-Derived iPSC (LMNA G608G Progeria / WRN Werner) / CRISPR Models
Disease modelling
No SOP yet
BRAIN
Publication-derived

Brain Organoids for Disease Modelling with Microglia

Source Ormel et al. · University Medical Center Utrecht, Netherlands · DOI

Duration: 52 days Cell source: Human iPSC
No SOP yet
BRAIN
Publication-derived

Zika Virus Infection Cortical 2D Cell Cultures

Source Cugola et al. · University of São Paulo (USP), São Paulo, Brazil · DOI

Duration: 35 days Cell source: Human iPSC Full SOP · 11 phases · QC included
Disease modelling
Full SOP with Academic or a plan
BRAIN
Publication-derived

Brain Organoids at Air-Liquid Interface

Source Giandomenico et al. · MRC Laboratory of Molecular Biology, Cambridge, UK · DOI

Duration: 135 days Cell source: Human iPSC / ESC Full SOP · 9 phases · QC included
Full SOP with Academic or a plan
BRAIN
Publication-derived

Brain Organoids for Regenerative Medicine

Source Mansour et al. · Salk Institute for Biological Studies, La Jolla, CA, USA · DOI

Duration: 240 days Cell source: Human iPSC / ESC
Regenerative medicine
No SOP yet
BRAIN
Publication-derived

Cerebral Organoids for Drug Screening with Electrophysiology

Source Watanabe et al. · Stanford University / Cincinnati Children's Hospital, USA · DOI

Duration: 150 days Cell source: Human iPSC (GCaMP6f Reporter Lines) Full SOP · 5 phases · QC included
Drug screening
Full SOP with Academic or a plan
BRAIN
Publication-derived

Brain Organoids with Electrophysiology

Source Trujillo et al. · University of California San Diego (UCSD), La Jolla, CA, USA · DOI

Duration: 300 days Cell source: Human iPSC
No SOP yet
BRAIN
Publication-derived

Brain Reference Datasets

Source Bhaduri et al. · University of California San Francisco (UCSF) / UCLA, USA · DOI

Duration: 120 days Cell source: Human iPSC
No SOP yet
BRAIN
Publication-derived

Brain Cancer Tumouroids

Source Eisemann et al. · University of Freiburg, Freiburg, Germany

Duration: 60 days Cell source: Patient-Derived GBM Tissue (MGMT Methylated vs. Unmethylated)
Regenerative medicine
No SOP yet
BRAIN
Publication-derived

Brain Organoids for Disease Modelling (2018)

Source Bian et al. · IMBA — Institute of Molecular Biotechnology, Vienna, Austria · DOI

Duration: 60 days Cell source: Human ESC (CRISPR-Edited: TP53, PTEN, NF1, CDKN2A)
No SOP yet
BRAIN
Publication-derived

Glioblastoma Brain Organoids

Source Linkous et al. · Howard Hughes Medical Institute / Yale University, USA · DOI

Duration: 28 days Cell source: Patient-Derived Glioma Stem Cells + Normal iPSC Cerebral Organoids Full SOP · 8 phases · QC included
Full SOP with Academic or a plan
BRAIN
Publication-derived

Brain Organoids for Drug Screening with Blood-Brain Barrier

Source Zhu et al. · Memorial Sloan Kettering Cancer Center, New York, USA · DOI

Duration: 21 days Cell source: Patient-Derived Brain Metastasis Tissue
Drug screening
No SOP yet
BRAIN
Publication-derived

Brain Organoids for Biobanking

Source Jacob et al. · University of Pennsylvania, Philadelphia, PA, USA · DOI

Duration: 14 days Cell source: Patient-Derived Primary GBM Tissue (Biobank, >70 Patients) Full SOP · 5 phases · QC included
Full SOP with Academic or a plan
BRAIN
Publication-derived

Zika Virus Infection Brain Models

Source Garcez et al. · Federal University of Rio de Janeiro (UFRJ), Brazil

Duration: 30 days Cell source: Human iPSC
Disease modelling
No SOP yet
BRAIN
Publication-derived

Down Syndrome Brain Organoids

Source Tang et al. · Icahn School of Medicine at Mount Sinai, New York, USA · DOI

Duration: 90 days Cell source: Patient-Derived iPSC (Trisomy 21) / Isogenic Disomic Controls
Disease modelling
No SOP yet
BRAIN
Publication-derived

Brain Models for Disease Modelling with Gene Editing

Source Blair et al. · University of Michigan, Ann Arbor, MI, USA · DOI

Duration: 150 days Cell source: Patient-Derived iPSC (TSC2+/-) / CRISPR TSC1/TSC2 Knockout Full SOP · 10 phases · QC included
Disease modelling
Full SOP with Academic or a plan
BRAIN
Publication-derived

Rett Syndrome Brain Models

Source Gomes et al. · University of California San Diego (UCSD), La Jolla, CA, USA · DOI

Duration: 180 days Cell source: Patient-Derived iPSC (MECP2 Mutations) / Isogenic Controls Full SOP · 9 phases · QC included
Disease modelling
Full SOP with Academic or a plan
BRAIN
Publication-derived

Brain Assembloids for Regenerative Medicine

Source Revah et al. · Stanford University School of Medicine, Stanford, CA, USA · DOI

Duration: 240 days Cell source: Human iPSC
Regenerative medicine
No SOP yet
BRAIN
Publication-derived

Brain Assembloids for Disease Modelling with Vasculature

Source Cakir et al. · Yale University, New Haven, CT, USA · DOI

Duration: 70 days Cell source: Human iPSC (+ ETV2-Inducible Endothelial Cells)
No SOP yet
BRAIN
Publication-derived

Brain Assembloids for Disease Modelling with Interneurons

Source Birey et al. · Stanford University School of Medicine, Stanford, CA, USA · DOI

Duration: 90 days Cell source: Human iPSC Full SOP · 4 phases · QC included
Disease modelling
Full SOP with Academic or a plan
BRAIN
Publication-derived

Cortical Assembloids for Developmental Studies

Source Ozair et al. · Memorial Sloan Kettering Cancer Center, New York, USA

Duration: 50 days Cell source: Human ESC / Human iPSC
Developmental biology
No SOP yet
BRAIN
Publication-derived

Brain Assembloids

Source Workman et al. · Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA · DOI

Duration: 70 days Cell source: Human iPSC Full SOP · 5 phases · QC included
Full SOP with Academic or a plan